Computational Laboratory for the Development of New Approaches to Complex Biological Phenomena

计算生物学中心将把建模和计算扩展到真实的生物过程中，特别是在分子生物物理学、分子遗传学、发育控制和进化等领域。三个主要的研究项目集中在蛋白质折叠和模拟，盘基骨的发育和核酸的杂交和折叠建模。将使用MonteCarlo，随机自动机和动态规划的当前方法。新的模拟概念将导致对复杂问题的更好理解，这些问题涉及对生物系统进行定量有效的预测。这个基础广泛的设施将推动计算生物学领域的发展，这对生物学家来说越来越有必要跟踪和理解日益复杂的数据。

AbstractDBI 9970199Onuchic, JoseComputational Laboratory for the Development of new Approaches to Complex Biological PhenomenaA computational biology center will extend modeling and computation to real biological processes especially in the area of molecular biophysics, molecular genetics, developmental control and evolution. The three primary research projects concentrate on protein folding and simulation, modeling Dictyostelium development and hybridization and folding of nucleic acids. Current methodologies of MonteCarlo, stochastic automata and dynamic programming will be used. New simulation concepts will lead to a better understanding of the complicated issues involved in making quantitatively valid predictions for biological systems. This broadly based facility will advance the field of computational biology, which is becoming increasingly necessary for biologists to keep track of and make sense of data of ever increasing complexity.