The Human Blueprint

人类蓝图

• 批准号: 0000611
• 负责人: Paula Apsell
• 金额: $ 55.28万
• 依托单位: WGBH Educational Foundation
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-06-01 至 2002-11-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0000611&HistoricalAwards=false
• 关键词: Human; Blueprint

0000611APSELLWGBH is producing a two-hour NOVA special that will examine the scientific undertaking to decipher all three billion letters of the human genetic code. The program will take viewers inside the labs where this effort is going on and will examine the difficult decisions that are arising from our growing understanding of the human genome. The central narrative thread in "The Human Blueprint" is the extraordinary race now going on between two teams striving to be the first to read, or "sequence," the human genome. On one side is the official Human Genome Project, funded by the federal government and coordinated by the National Human Genome Research Institute; on the other side is private industry, in the form of a well-financed company run by a biologist with a long track record of finding quicker, cheaper ways to plumb the secrets of the genetic code. To support the extended use of the series, "The Human Blueprint" will be featured in the NOVA teachers guide and will be the subject of an enhanced Web sit at NOVA Online.The Executive Producer for the programs will be Paula Apsell, Executive Producer for NOVA, and the series will be produced by Elizabeth Arledge who has produced science programming for WGBH, WNET and CBS News. Dr. Joseph Levine will serve as science consultant to "The Human Blueprint" and will work with the producer to plan program research, suggest sequence possibilities, review program treatments and critique the film at early stages. Dr. Levine has a Ph.D. in Biology from Harvard University and served as the science editor for the WGBH series "The Secret of Life." Advisors to the series include: W. French Anderson, Professor of Biochemistry and Pediatrics and the Director of Gene Therapy Laboratories at the University of Southern California School of MedicineDavid Baltimore, President of the California Institute of Technology and Chairman of the NIH AIDS Vaccine Research Committee Paul Berg, Director of the Beckman Center for Molecular and Genetic Research at Stanford UniversityRobin Blatt, Founder of the Genetic Resource at the Massachusetts Health Research InstituteDavid Blumenthal, Director of the Institute for Health Policy and Professor of Medicine and Health Care Policy at Harvard Medical School and Massachusetts General HospitalRobert Cook-Deegan, Director of the National Cancer Policy Board, Institute of Medicine and the Commission on Life Sciences of the National Academy of SciencesRonald G. Crystal, Director of the Gene Therapy Core facility at Cornell University Medical CollegeGeorgia M. Dunston, Professor of Microbiology and Acting Director of the National Human Genome Center at Howard UniversityPhilip R. Reilly, Executive Director of the Shriver Center for Mental RetardationLydia Villa-Komaroff, Vice President of Research and Professor of Neurology at Northwestern University

0000611APSELLWGBH正在制作一个两小时的NOVA特别节目，将研究破译人类遗传密码所有30亿个字母的科学事业。该节目将带领观众进入正在进行这项工作的实验室，并将审视我们对人类基因组日益了解所产生的困难决定。《人类蓝图》的中心叙事线索是两个团队之间正在进行的非同寻常的竞赛，他们都在努力成为第一个读取或“排序”人类基因组的团队。一方面是由联邦政府资助并由国家人类基因组研究所协调的官方人类基因组计划；另一边是私营企业，其形式是一家资金雄厚的公司，由一位生物学家经营，长期以来，他一直在寻找更快、更便宜的方法来探索遗传密码的秘密。为了支持该系列的扩展使用，“人类蓝图”将成为NOVA教师指南的特色，并将成为NOVA在线增强Web站点的主题。节目的执行制片人将是新星电视台的执行制片人保拉·阿普塞尔，该剧的制片人将是伊丽莎白·阿利奇，她曾为WGBH、WNET和CBS新闻制作过科学节目。约瑟夫·莱文博士将担任《人类蓝图》的科学顾问，并将与制片人一起计划节目研究，建议序列可能性，审查节目处理，并在早期阶段对电影进行评论。莱文博士拥有哈佛大学生物学博士学位，曾担任WGBH系列“生命的秘密”的科学编辑。该系列的顾问包括：W. French Anderson，生物化学和儿科教授，南加州大学医学院基因治疗实验室主任，david Baltimore，加州理工学院院长，美国国立卫生研究院艾滋病疫苗研究委员会主席，Paul Berg，斯坦福大学贝克曼分子和基因研究中心主任，robin Blatt，麻省卫生研究所遗传资源创始人，david Blumenthal，哈佛医学院和麻省总医院卫生政策研究所所长、医学和卫生保健政策教授robert Cook-Deegan、国家癌症政策委员会主任、医学研究所和国家科学院生命科学委员会主任ronald G. Crystal、康奈尔大学医学院基因治疗核心设施主任georgia M. Dunston、霍华德大学微生物学教授兼国家人类基因组中心代理主任philip R. Reilly，施莱弗精神发育迟缓中心执行主任lydia Villa-Komaroff，西北大学研究副主席兼神经学教授