Acqusition of a 400-MHz NMR Spectrometer for Use in Research and Research Training in Chemistry at Oberlin College

购买 400 MHz NMR 波谱仪，用于欧柏林学院化学研究和研究培训

• 批准号: 0079470
• 负责人: Manish Mehta
• 金额: $ 25.2万
• 依托单位: Oberlin College
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-09-01 至 2004-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0079470&HistoricalAwards=false
• 关键词: Acqusition; 400; MHz; NMR; Spectrometer

With support from the Major Research Instrumentation (MRI) Program, the Department of Chemistry at Oberlin College will acquire a 400 MHz NMR Spectrometer. This equipment will enable researchers to carry out studies on a) peptide-surface interactions and engineered biomaterials; b) direct measurement of secondary structure in a membrane receptor-ligand complex; c) coordination chemistry of alpha-azoimines; d) asymmetric catalysts; and e) mechanistic and synthetic studies of oxyallyl intermediates. Nuclear Magnetic Resonance (NMR) spectroscopy is the most powerful tool available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectrometry is essential to chemists who are carrying out frontier research. The results from these NMR studies will have an impact in a number of areas including biological chemistry.

在主要研究仪器(MRI)计划的支持下，奥伯林学院化学系将获得一台400 MHz核磁共振光谱仪。该设备将使研究人员能够开展以下方面的研究：a)肽-表面相互作用和工程生物材料；b)膜受体-配体复合体的二级结构的直接测量；c)α-偶氮亚胺的配位化学；d)不对称催化剂；以及e)氧烯丙基中间体的机理和合成研究。核磁共振波谱是化学家用来解释分子结构的最有力的工具。它被用来识别未知物质，表征分子内原子的特定排列，并研究溶液中分子之间相互作用的动力学。对于正在进行前沿研究的化学家来说，获得最先进的核磁共振光谱是必不可少的。这些核磁共振研究的结果将对包括生物化学在内的许多领域产生影响。