Physiological Bases for Long Term Effects of Winning
获胜的长期影响的生理基础
基本信息
- 批准号:0110625
- 负责人:
- 金额:$ 31.95万
- 依托单位:
- 依托单位国家:美国
- 项目类别:Standard Grant
- 财政年份:2001
- 资助国家:美国
- 起止时间:2001-08-01 至 2006-12-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
. LAY ABSTRACTUnderstanding how past experience shapes future behavior is one of the fundamental challenges for modern animal behavior and neurobiology. Meeting this challenge will require characterization of physiological changes triggered by experiences known to influence specific behaviors, such as aggression during male-male encounters. Two factors have been shown to critically influence the intensity of aggression expressed in an encounter: 1) the outcomes of previous encounters, whether won or lost, and 2) the location of the encounter, whether familiar or unfamiliar. It is the goal of the proposed work to examine the physiological components that contribute to the effect winning has on future encounters (winner effect), as well as those components that contribute to aggression associated with familiarity with the encounter location. Specifically, the function of observed changes in testosterone after competitive interactions will be evaluated. In addition, neurochemical changes that occur in response to transient changes in testosterone will be documented. To begin examining the role of site familiarity in the intensity of aggression, comparisons will be made between resident-intruder aggression (site-specific aggression) and neutral aggression (aggression in a neutral arena). It is predicted that the neurochemical vasopressin will be more closely associated with resident-intruder aggression than neutral aggression. The monogamous, highly parental Peromyscus californicus (California mouse), and the promiscuous, less parental P. leucopus (white-footed mouse) will be developed as model systems for this analysis of interactions between experience and intensity of aggression. Information obtained in these studies may provide insight into some of the physiological mechanisms underlying plasticity in the intensity of aggression in mammals.
.了解过去的经验如何塑造未来的行为是现代动物行为和神经生物学的基本挑战之一。 应对这一挑战将需要表征已知会影响特定行为的经历所引发的生理变化,例如男性与男性相遇时的侵略行为。 两个因素已经被证明对遭遇战中表现出的攻击强度有关键影响:1)以前遭遇战的结果,无论是赢还是输,以及2)遭遇战的地点,无论是熟悉还是不熟悉。 这是所提出的工作的目标,以检查的生理成分,有助于赢得对未来的遭遇(赢家效应)的影响,以及那些组件,有助于侵略与熟悉的遭遇地点。 具体而言,将评价竞争性相互作用后观察到的睾酮变化的功能。 此外,将记录因睾酮一过性变化而发生的神经化学变化。 为了开始研究地点熟悉度在攻击强度中的作用,我们将对居民-入侵者攻击(地点特异性攻击)和中性攻击(中性竞技场中的攻击)进行比较。 据预测,神经化学加压素将更密切地与居民入侵者的攻击比中性攻击。 将一夫一妻制的、高度亲源性的Peromyscus californicus(加州小鼠)和混杂的、亲源性较低的P. leucopus(白足小鼠)作为模型系统开发,用于分析攻击性经验和强度之间的相互作用。在这些研究中获得的信息可能会提供洞察的一些生理机制的可塑性的强度在哺乳动物的侵略。
项目成果
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Catherine Marler其他文献
Oxytocin impairs wound-healing during social isolation but not social living
在社会隔离期间,催产素会损害伤口愈合,但在群居生活中则不会。
- DOI:
10.1016/j.psyneuen.2025.107445 - 发表时间:
2025-06-01 - 期刊:
- 影响因子:3.600
- 作者:
Emma Hammond;Patrick Monari;Lila Kilponen;Yiru Chen;Anthony Auger;Catherine Marler - 通讯作者:
Catherine Marler
Catherine Marler的其他文献
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{{ truncateString('Catherine Marler', 18)}}的其他基金
Mechanisms of Behavioral Synchrony and Division of Labor in a Monogamous Mammalian Species, the California Mouse
一夫一妻制哺乳动物加州小鼠的行为同步和分工机制
- 批准号:
1946613 - 财政年份:2020
- 资助金额:
$ 31.95万 - 项目类别:
Standard Grant
The effect of testosterone pulses and conditioned place preferences on social behavior in wild and laboratory Peromyscus mice
睾酮脉冲和条件性位置偏好对野生和实验室白鼠社交行为的影响
- 批准号:
1355163 - 财政年份:2014
- 资助金额:
$ 31.95万 - 项目类别:
Continuing Grant
DISSERTATION RESEARCH: Male testosterone response to courtship in the monogamous California mouse: an honest signal of paternal quality?
论文研究:一夫一妻制的加州小鼠雄性睾酮对求爱的反应:父系品质的诚实信号?
- 批准号:
1010799 - 财政年份:2010
- 资助金额:
$ 31.95万 - 项目类别:
Standard Grant
Cross-Generational Transmission of Aggression: Behavioral, Hormonal and Neural Mechanisms
攻击性的跨代传递:行为、激素和神经机制
- 批准号:
0620042 - 财政年份:2006
- 资助金额:
$ 31.95万 - 项目类别:
Continuing Grant
CAREER: The Social Environment and Developmental Plasticityin Vasopressin Neurochemical Pathways
职业:加压素神经化学途径的社会环境和发育可塑性
- 批准号:
9703309 - 财政年份:1997
- 资助金额:
$ 31.95万 - 项目类别:
Continuing Grant
RPG: Neuropeptide Control of Territorial Aggression
RPG:神经肽控制领土攻击
- 批准号:
9407691 - 财政年份:1994
- 资助金额:
$ 31.95万 - 项目类别:
Standard Grant
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