MRI: Acquisition of a 300 MHz FT-NMR for Undergraduate Research and Training

MRI：获取 300 MHz FT-NMR 用于本科生研究和培训

• 批准号: 0116100
• 负责人: Shaun Murphree
• 金额: $ 18.8万
• 依托单位: Allegheny College
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-08-15 至 2004-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0116100&HistoricalAwards=false
• 关键词: MRI; Acquisition; 300; MHz; FT

With this award from the Major Research Instrumentation (MRI) Program, the Department of Chemistry at Allegheny College will acquire a 300 MHz Fourier-Transform Nuclear Magnetic Resonance (FT-NMR) Spectrometer. This equipment will enable researchers to carry out studies on a) development of new methods for the synthesis of sulfones; b) synthesis of natural products; c) study of active centers in metalloproteins; d) development of models to predict the stability of RNA structure from sequence; e) development of novel complexes to catalyze oxidation reactions of biological, chemical and environmental relevance. This instrument will be used for undergraduates in their research and also within the curriculum. Nuclear Magnetic Resonance (NMR) spectroscopy is the most powerful tool available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectrometers is essential to chemists who are carrying out frontier research. The results from these NMR studies will have an impact in a number of areas including environmental chemistryand biochemistry.

从主要研究仪器（MRI）计划的这一奖项，在阿勒格尼学院化学系将获得300兆赫傅里叶变换核磁共振（FT-NMR）光谱仪。该设备将使研究人员能够进行以下研究：a）开发合成砜的新方法; B）合成天然产物; c）研究金属蛋白中的活性中心; d）开发模型，从序列预测RNA结构的稳定性; e）开发新型复合物，以催化与生物、化学和环境相关的氧化反应。 该仪器将用于本科生在他们的研究，也在课程。 核磁共振（NMR）光谱是化学家用来阐明分子结构的最有力的工具。它用于识别未知物质，表征分子内原子的特定排列，并研究溶液中分子之间相互作用的动力学。 对于从事前沿研究的化学家来说，使用最先进的NMR光谱仪是必不可少的。这些核磁共振研究的结果将在许多领域产生影响，包括环境化学和生物化学。