Biophotonics: Spatially-Controlled Stem Cell Differentiation by Laser-Guided Direct Writing of Bioactive Materials
Biophotonics: Spatially-Controlled Stem Cell Differentiation by Laser-Guided Direct Writing of Bioactive Materials
批准号:
0119481
负责人:
David Odde
金额:
$41.31万
依托单位国家:
美国
项目类别:
Standard Grant
财政年份:
2001
资助国家:
美国
项目状态:
已结题
起止时间:
2001-09-01 至 2006-02-28
中文摘要
本项目的目标是使用LGDW将血管内皮生长因子(VEGF)包裹的微球输送到未分化的多潜能成体祖细胞(MAPC),以诱导局部的内皮(血管衬里)细胞表型。将研究的颗粒材料包括聚苯乙烯和聚乳酸-乙醇酸,尺寸从1-10微米不等。血管内皮生长因子将通过商业上可用的表面化学方法共价固定在颗粒上。
英文摘要
0119481OddeThe objective of this project will be to use LGDW to deliver vascular-endothelial growth factor (VEGF)-coated microspheres to undifferentiated multipotent adult progenitor cells (MAPCs) to induce the endothelial (blood vessel lining) cell phenotype locally. The particle materials to be studied will include polystyrene and polylactic-glycolic acid with sizes ranging from 1-10 um. VEGF will be covalently immobilized to the particles via commercially available surface chemistry.
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会议论文
Chemical and Mechanical Interactions in Microtubules
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批准号:0615568
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项目类别:Standard Grant
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资助金额:$52.53万
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财政年份:2006
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负责人:David Odde
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依托单位:
Micromechanical Engineering of Connectivity in Living Neural Networks
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批准号:0130875
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项目类别:Continuing Grant
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资助金额:$40.0万
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财政年份:2002
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负责人:David Odde
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依托单位:
CAREER: Microtubule Severing Mechanisms
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批准号:9984955
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项目类别:Standard Grant
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资助金额:$20.0万
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财政年份:2000
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负责人:David Odde
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依托单位:
SGER: Laser-Guided Direct Writing of Multipotent Adult Stem Cells
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批准号:0092810
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项目类别:Standard Grant
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资助金额:$9.91万
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财政年份:2000
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负责人:David Odde
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依托单位:
Chemical and Mechanical Interactions in Microtubules
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批准号:9710354
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项目类别:Standard Grant
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资助金额:$9.02万
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财政年份:1997
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负责人:David Odde
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依托单位:
Integrated Bioprocess Experiments for the Undergraduate Chemical Engineering Curriculum
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批准号:9750570
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项目类别:Standard Grant
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资助金额:$2.13万
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财政年份:1997
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负责人:David Odde
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依托单位:
海外基金