GOALI: MEMS Based Sensors and Actuators for Medical and Biological Applications

GOALI：用于医疗和生物应用的基于 MEMS 的传感器和执行器

• 批准号: 0201773
• 负责人: Frank Lewis
• 金额: $ 23.51万
• 依托单位: University of Texas at Arlington
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-10-01 至 2006-09-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0201773&HistoricalAwards=false
• 关键词: GOALI; MEMS; Based; Sensors; Actuators

0201773LewisMechanical ventilators play critical roles in saving lives of patients with pulmonary dysfunction. Emergency manual resuscitators are used daily by paramedics to revive trauma patients. For life support these devices must sense respiratory pressures. Size and electric power requirements of current pressure transducers restrict sensing of pressures to points within the machine and distal to patient airways. This can severely degrade the efficacy of the ventilator or even create patient trauma, as the natural airway anatomical variability creates unpredictable pressure losses. Moreover, chronic pulmonary illnesses due to air pollution and asthma are increasing. To understand and quantify the effects on respiration, better sensors are needed.This GOALI proposal focuses on designing, fabricating and testing in vivo novel microelectromechanical systems (MEMS) pressure and flow sensors based purely on optics that can be deployed into the airways, e.g. into endotracheal tubes, nasal masks, ventilators and resuscitators. The research team, which includes collaborations between three academic units and three industrial partners, will perform fundamental research in detecting sensor activation effects using purely optical techniques and will develop new design, analysis, testing, calibration, and production practices for optical MEMS biosensors. New digital signal processing approaches will be developed to obtain required accuracies and ranges of measurement. .As part of the outreach plan, the GOALI team will 1) develop a new design course on MEMS sensor and actuator analysis, design, prototyping, and applications, including biomedical, 2) develop courseware that can be used over the internet for training of industry engineers and students and 3) offer two industrial seminars on-site at industrial partners.

0201773Lewis机械呼吸机在挽救肺功能障碍患者的生命方面发挥着关键作用。护理人员每天使用紧急手动复苏器来抢救创伤患者。为了维持生命，这些设备必须感知呼吸压力。当前压力传感器的尺寸和电力要求将压力感测限制在机器内和患者气道远端的点。这会严重降低呼吸机的功效，甚至造成患者创伤，因为自然气道解剖结构的变化会产生不可预测的压力损失。此外，由空气污染和哮喘引起的慢性肺部疾病也在增加。为了了解和量化对呼吸的影响，需要更好的传感器。该 GOALI 提案侧重于设计、制造和测试体内新型微机电系统 (MEMS) 压力和流量传感器，这些传感器纯粹基于可部署到气道中的光学器件，例如气道。进入气管插管、鼻罩、呼吸机和复苏器。 该研究团队由三个学术单位和三个工业合作伙伴组成，将利用纯光学技术进行传感器激活效应检测的基础研究，并将开发光学 MEMS 生物传感器的新设计、分析、测试、校准和生产实践。 将开发新的数字信号处理方法以获得所需的测量精度和范围。 作为推广计划的一部分，GOALI 团队将 1) 开发关于 MEMS 传感器和执行器分析、设计、原型设计和应用（包括生物医学）的新设计课程，2) 开发可通过互联网用于培训行业工程师和学生的课件，3) 在工业合作伙伴现场提供两场工业研讨会。