Conference on Plant Biology: Functions and Control of Cell Death; to be held April 10-16, 2003; Snowbird, Utah

植物生物学会议：细胞死亡的功能和控制；

• 批准号: 0228340
• 负责人: Jeffery Dangl
• 金额: $ 1.8万
• 依托单位: Keystone Symposia on Molecular and Cellular Biology
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-03-15 至 2004-02-29
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0228340&HistoricalAwards=false
• 关键词: Conference; Plant; Biology; Functions; Control

0228340DanglThis meeting will impact several very diverse areas of plant science, from disease and disease resistance to various aspects of plant cell death control during normal development and response to plant hormones. As such, the meeting will attract a very diverse audience. Programmed cell deaths occur at many stages in normal plant growth and development, and is also induced during successful response to infection (the common hypersensitive response) and in response to abiotic stress, particularly those stress responses involving reactive oxygen intermediates. Yet, despite the physiological characterization of a variety of programmed cell deaths over the last 20 years, very little is know about the molecular control of either cell death signaling or cell execution. Moreover, analyses of the complete Arabidopsis and draft rice genomic sequences show that there are no obvious homologues of the common animal cell death control genes in plants. Nevertheless, several studies have shown that expression of animal anti- or pro-cell death control genes in plants can either block or exacerbate plant cell death, respectively. These data argue that some of the mechanisms may be shared between plant and animal cell death control. The meeting proposed will address these issues. This interdisciplinary meeting will result in much cross feeding of disciplines as diverse as plant hormone physiology and plant genomics. A broad participant portfolio with respect to organism studied and biological question asked is assured. The meeting will stress the notion that research in easily accessible models must be translated to scientists applying that basic knowledge to crop plant biology. Thus, the meeting will foster translational agriculture. In order to achieve this goal, the organizers will select participants with broad sets of educational and experiential backgrounds. As part of this aspect of designing the meeting, they will be particularly aware of increasing participation of women, under-represented ethnic groups, and under-represented institutions of higher learning. The speakers include nearly every relevant female principal investigator working in this arena today. The Keystone Symposia are very educationally and community oriented and the selection criteria will include the ideal of capturing the widest participant pool possible while maintaining scientific excellence. The Keystone Symposia are advertised by direct mailings to a huge number of higher educational institutions and the organizers have already received inquiries from potential participants from very "out of the way" universities and colleges. Finally, and perhaps most critically, the organizers have included as many early career scientists as possible. In fact, this NSF award will go exclusively to defraying the costs of doctoral students and non-tenured principal investigators. The organizers will prioritize these to fund as many participants as possible from non-standard research I universities, and will use the guidelines established above to guide our choices.

0228340 Dangl这次会议将影响植物科学的几个非常不同的领域，从疾病和抗病性到正常发育过程中植物细胞死亡控制的各个方面和对植物激素的反应。因此，会议将吸引各种各样的听众。程序性细胞死亡发生在植物正常生长发育的许多阶段，也可在对感染的成功反应（常见的过敏反应）和对非生物胁迫的反应中诱导，特别是那些涉及活性氧中间体的胁迫反应。然而，尽管在过去的20年里，各种程序性细胞死亡的生理特征，很少有人知道细胞死亡信号或细胞执行的分子控制。此外，完整的拟南芥和水稻基因组序列的分析表明，没有明显的同源物的共同动物细胞死亡控制基因在植物中。然而，一些研究表明，动物抗或促细胞死亡控制基因在植物中的表达可以分别阻止或加剧植物细胞死亡。这些数据表明，植物和动物细胞死亡控制之间的一些机制可能是共享的。拟议的会议将讨论这些问题。 这个跨学科的会议将导致许多交叉喂养的学科，如植物激素生理学和植物基因组学。一个广泛的参与者投资组合方面的有机体研究和生物学问题提出的保证。会议将强调这样一个概念，即在容易获得的模型中进行的研究必须转化为科学家将这些基本知识应用于作物植物生物学。因此，会议将促进转化农业。 为了实现这一目标，组织者将选择具有广泛教育和经验背景的参与者。作为设计会议的这一方面的一部分，他们将特别意识到妇女、代表性不足的族裔群体和代表性不足的高等教育机构越来越多地参与。发言者包括几乎所有相关的女性主要研究人员在这个竞技场今天的工作。基石研讨会是非常教育和社区为导向，选择标准将包括捕捉尽可能广泛的参与者池，同时保持科学卓越的理想。Keystone专题讨论会通过直接邮寄的方式向大量高等教育机构做广告，组织者已经收到了来自非常“偏僻”的大学和学院的潜在参与者的询问。 最后，也许也是最关键的一点，组织者尽可能多地邀请了早期的职业科学家。事实上，这个NSF奖项将专门用于支付博士生和非终身首席研究员的费用。组织者将优先考虑这些，以资助尽可能多的非标准研究型大学的参与者，并将使用上述指南来指导我们的选择。