Conference on Plant Biology: Functions and Control of Cell Death; to be held April 10-16, 2003; Snowbird, Utah

[02:28 . 34]这次会议将影响植物科学的几个非常多样化的领域，从疾病和抗病性到植物正常发育过程中细胞死亡控制的各个方面以及对植物激素的反应。因此，会议将吸引非常多样化的听众。细胞程序性死亡发生在植物正常生长发育的许多阶段，在成功应对感染（常见的超敏反应）和应对非生物胁迫（特别是涉及活性氧中间体的胁迫反应）时也会引起细胞程序性死亡。然而，尽管在过去的20年里，各种程序性细胞死亡的生理特征得到了揭示，但对细胞死亡信号或细胞执行的分子控制知之甚少。此外，对拟南芥和水稻的全基因组序列分析表明，植物中没有明显的动物细胞死亡控制基因的同源性。然而，一些研究表明，动物抗或促细胞死亡控制基因在植物中的表达分别可以阻止或加剧植物细胞死亡。这些数据表明，植物和动物细胞死亡控制的一些机制可能是相同的。提议召开的会议将讨论这些问题。这个跨学科的会议将导致许多学科的交叉喂养，如植物激素生理学和植物基因组学。一个广泛的参与者组合关于生物体的研究和生物学问题提出了保证。会议将强调这样一个概念，即在容易获得的模型中进行的研究必须转化为科学家将这些基本知识应用于作物植物生物学。因此，会议将促进转化农业。为了实现这一目标，组织者将选择具有广泛教育和经验背景的参与者。作为设计会议这一方面的一部分，他们将特别注意到妇女、代表性不足的族裔群体和代表性不足的高等院校的参与日益增加。演讲者几乎包括当今在这一领域工作的所有相关女性首席研究员。Keystone专题讨论会以教育和社区为导向，选择标准将包括在保持科学卓越的同时尽可能吸引最广泛的参与者。Keystone研讨会的广告是通过直接邮寄给大量高等教育机构的，组织者已经收到了来自非常“偏僻”的大学和学院的潜在参与者的咨询。最后，或许也是最关键的一点是，组织者尽可能多地吸纳了早期职业科学家。事实上，这个国家科学基金会的奖励将专门用于支付博士生和非终身首席研究员的费用。组织者将优先考虑这些，以资助来自非标准研究型大学的尽可能多的参与者，并将使用上述指导方针来指导我们的选择。

0228340DanglThis meeting will impact several very diverse areas of plant science, from disease and disease resistance to various aspects of plant cell death control during normal development and response to plant hormones. As such, the meeting will attract a very diverse audience. Programmed cell deaths occur at many stages in normal plant growth and development, and is also induced during successful response to infection (the common hypersensitive response) and in response to abiotic stress, particularly those stress responses involving reactive oxygen intermediates. Yet, despite the physiological characterization of a variety of programmed cell deaths over the last 20 years, very little is know about the molecular control of either cell death signaling or cell execution. Moreover, analyses of the complete Arabidopsis and draft rice genomic sequences show that there are no obvious homologues of the common animal cell death control genes in plants. Nevertheless, several studies have shown that expression of animal anti- or pro-cell death control genes in plants can either block or exacerbate plant cell death, respectively. These data argue that some of the mechanisms may be shared between plant and animal cell death control. The meeting proposed will address these issues. This interdisciplinary meeting will result in much cross feeding of disciplines as diverse as plant hormone physiology and plant genomics. A broad participant portfolio with respect to organism studied and biological question asked is assured. The meeting will stress the notion that research in easily accessible models must be translated to scientists applying that basic knowledge to crop plant biology. Thus, the meeting will foster translational agriculture. In order to achieve this goal, the organizers will select participants with broad sets of educational and experiential backgrounds. As part of this aspect of designing the meeting, they will be particularly aware of increasing participation of women, under-represented ethnic groups, and under-represented institutions of higher learning. The speakers include nearly every relevant female principal investigator working in this arena today. The Keystone Symposia are very educationally and community oriented and the selection criteria will include the ideal of capturing the widest participant pool possible while maintaining scientific excellence. The Keystone Symposia are advertised by direct mailings to a huge number of higher educational institutions and the organizers have already received inquiries from potential participants from very "out of the way" universities and colleges. Finally, and perhaps most critically, the organizers have included as many early career scientists as possible. In fact, this NSF award will go exclusively to defraying the costs of doctoral students and non-tenured principal investigators. The organizers will prioritize these to fund as many participants as possible from non-standard research I universities, and will use the guidelines established above to guide our choices.