The Plant Ontology Consortium

植物本体联盟

• 批准号: 0321666
• 负责人: Lincoln Stein
• 金额: $ 167.24万
• 依托单位: Cold Spring Harbor Laboratory
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-09-01 至 2007-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0321666&HistoricalAwards=false
• 关键词: Plant; Ontology; Consortium

This project supports the operations of the Plant Ontology Consortium (POC). The goals of the POC are to develop a common set of controlled vocabulary terms to describe anatomic and developmental stage terms in both experimental and agronomically important plants. We have begun with Arabidopsis and cereals, and will later extend this ontology to encompass legumes, Solanaceae, and other families. Concurrently, we are applying these terms to the task of describing the genes and mutants that are contained within the plant-specific databases maintained by the participating institutions, thereby simultaneously refining the ontologies, and providing points of reference with which to compare the genes and mutants across these species.The broader impact of this project is that it provides a framework of plant development to allow researchers to make meaningful cross-database queries across the various species-specific resources in order to discover patterns of similarities and dissimilarities involved in plant development. For example, researchers will be able to obtain a definitive list of genes whose action affects plant stem development. The interaction between research communities will be facilitated by a "Rosetta stone" that bridges their historical differences in terminology. This will allow the fruits of research in one plant species to be more easily used in the study of other species, leading to a greater understanding of plant biology. This in turn will aid in the creation of new varieties of crop plants to meet the food needs of an ever-growing world population, to the development of pharmaceuticals to treat human disease, and the creation of new classes of herbicides, pesticides and biological control measure to counter the growing impact of resistant weeds and pests on world-wide agriculture.DeliverablesDeliverables from this project include: (a) an ontology describing plant anatomy; (b) an ontology describing plant developmental stages; (c) a web site that stores plant ontology associations to strains, mutants and genes from multiple participant databases; (d) a series of users group meetings that provide education and outreach opportunities.

该项目支持植物本体联盟（POC）的运作。 POC的目标是开发一套通用的受控词汇术语，以描述实验和农学上重要植物的解剖和发育阶段术语。 我们已经开始与拟南芥和谷物，稍后将扩展这个本体论，包括豆类，茄科，和其他家庭。 同时，我们将这些术语应用于描述参与机构维护的植物特定数据库中包含的基因和突变体的任务，从而同时完善本体，该项目的更广泛影响是，它提供了一个植物发育的框架，使研究人员能够有意义的跨数据库查询，在各种物种的具体资源，以发现模式的相似性和不同之处，在植物发展。例如，研究人员将能够获得一份明确的基因清单，这些基因的作用会影响植物茎的发育。 研究界之间的互动将通过"罗塞塔石碑"来促进，该石碑弥合了它们在术语方面的历史差异。 这将使一种植物物种的研究成果更容易用于其他物种的研究，从而加深对植物生物学的了解。 这反过来将有助于创造新的作物品种，以满足日益增长的世界人口的粮食需求，有助于开发治疗人类疾病的药物，并有助于创造新的除草剂、杀虫剂和生物控制措施，以应对抗药性杂草和害虫对世界农业日益增长的影响。（a）描述植物解剖学的本体;（B）描述植物发育阶段的本体;（c）存储植物本体与来自多个参与者数据库的菌株、突变体和基因的关联的网站;（d）提供教育和推广机会的一系列用户组会议。