FIBR Planning: Why are so many Plants Polyploid?

FIBR 规划：为什么这么多植物是多倍体？

• 批准号: 0402372
• 负责人: Andrew Paterson
• 金额: $ 4.94万
• 依托单位: University of Georgia Research Foundation Inc
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-03-15 至 2005-02-28
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0402372&HistoricalAwards=false
• 关键词: FIBR; Planning; Why; so; many

Intellectual merit: This project focuses on a major, unanswered question in biology: Why are so many plants polyploid? The prevalence of polyploidy in plants and its rarity in animals represent a fundamental genomic distinction between these kingdoms. Genomic sequences for representatives of each of two major angiosperm branches (dicots: Arabidopsis and monocots: Oryza), together with new information from other taxa, provide new opportunities to examine the evolutionary significance of polyploidy and its abundance in angiosperms. An anticipated new synthesis about the role of polyploidy in evolution is expected to be generally relevant both to angiosperms and ancient polyploids in other kingdoms such as fungi and animals. Goals in this planning project are the assembly of a multidisciplinary team and the development of a comprehensive research plan. These goals are being pursued through a series of smaller meetings followed by a workshop. These meetings will enable participants to explore computational methods for inferring the antiquity of specific polyploidization events; the feasibility of linking resulting computational inferences to paleobotanical and paleoclimatological data; and wet-lab approaches to test new hypotheses about polyploidization in an array of taxa across the plant family tree. Broader impacts: This planning project includes the development of plans for opportunities to participate in cutting-edge integrative biology research opportunities at both pre- and postgraduate levels. This will be coupled with ongoing ties to strong outreach programs designed to effectively engage under-represented groups in the project. Additionally, plans will be developed for enhancing the research and education infrastructure by Web-based dissemination of deliverables valuable to a diverse clientele. Such materials are being developed through partnerships with unique programs at the participating institutions and by forging links among these programs. For example, through an NSF GK-12 program at UGA project participants will contribute actively to the development and implementation of new research-based educational materials. Together with ten GK-12 graduate students and an associated statewide network of high-school teachers, project participants are exploring metaphorical examples and dialogue by which to portray key scientific concepts. Materials will be developed for broad dissemination to enhance public understanding of science, both directly and via museums (such as the FL Museum of Natural History, with which three participants are associated), nature centers, and similar institutions.

智力价值：该项目重点关注生物学中一个尚未解答的重大问题：为什么这么多植物是多倍体？ 植物中多倍体的普遍性和动物中的罕见性代表了这些王国之间的基本基因组区别。 两个主要被子植物分支（双子叶植物：拟南芥和单子叶植物：稻）代表的基因组序列，以及来自其他类群的新信息，为研究多倍体的进化意义及其在被子植物中的丰度提供了新的机会。 关于多倍体在进化中的作用的预期新综合预计通常与被子植物和其他界（例如真菌和动物）中的古代多倍体相关。该规划项目的目标是组建多学科团队并制定全面的研究计划。这些目标是通过一系列小型会议和随后的研讨会来实现的。 这些会议将使参与者能够探索推断特定多倍体化事件的古老性的计算方法；将计算推论与古植物学和古气候学数据联系起来的可行性；以及湿实验室方法来测试有关植物谱系中一系列分类单元多倍化的新假设。 更广泛的影响：该规划项目包括制定在预科和研究生阶段参与尖端综合生物学研究机会的计划。这将与旨在有效吸引代表性不足的群体参与该项目的强有力的外展计划持续联系在一起。 此外，还将制定计划，通过基于网络传播对不同客户有价值的成果来加强研究和教育基础设施。 这些材料是通过与参与机构的独特项目合作以及在这些项目之间建立联系来开发的。 例如，通过 UGA 的 NSF GK-12 计划，项目参与者将积极为新的研究型教育材料的开发和实施做出贡献。 项目参与者与 10 名 GK-12 研究生和相关的全州高中教师网络一起探索隐喻示例和对话，以描绘关键的科学概念。 将开发用于广泛传播的材料，以直接或通过博物馆（例如与三位参与者相关的佛罗里达自然历史博物馆）、自然中心和类似机构，增强公众对科学的理解。