Acquisition of a 400 MHz NMR Spectrometer for the University of Tennessee at Chattanooga

为田纳西大学查塔努加分校采购一台 400 MHz NMR 波谱仪

• 批准号: 0420549
• 负责人: Gregory Grant
• 金额: $ 28万
• 依托单位: University of Tennessee Chattanooga
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-08-01 至 2007-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0420549&HistoricalAwards=false
• 关键词: Acquisition; 400; MHz; NMR; Spectrometer

With this award from the Major Research Instrumentation (MRI) Program, the Department of Chemistry at the University of Tennessee in Chattanooga will acquire a 400 MHz nuclear magnetic resonance (NMR) Spectrometer. This equipment will enable researchers to carry out studies on a) organometallic catalysis of stereoselective organic reactions; b) multinuclear analysis of heavy metal thioether complexes; c) reduction of organic compounds by catalytic transfer hydrogenation using Raney catalysts and hydrogen donors; d) the reactions mechanism of pyridinium chlorochromate oxidation of bis-homoallylic tertiary alcohols; and e) the effect of inhibitors on pyrimidine de novo biosynthetic pathway enzymes Nuclear Magnetic Resonance (NMR) spectroscopy is one of the most powerful tools available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectrometers is essential to chemists who are carrying out frontier research. The results from these NMR studies will have an impact in organometallic synthesis, natural products chemistry, biochemistry, complexation of heavy metals and physical organic chemistry.

有了这项来自主要研究仪器（MRI）计划的奖励，位于查塔努加的田纳西大学化学系将获得一台400 MHz核磁共振（NMR）光谱仪。该设备将使研究人员能够进行以下研究：a）立体选择性有机反应的有机金属催化; B）重金属硫醚络合物的多核分析; c）使用Raney催化剂和氢供体通过催化转移氢化还原有机化合物; d）氯铬酸吡啶鎓氧化双高烯丙基叔醇的反应机理;和e）抑制剂对嘧啶从头生物合成途径酶的作用 核磁共振（NMR）光谱是化学家用来阐明分子结构的最有力的工具之一。它用于识别未知物质，表征分子内原子的特定排列，并研究溶液中分子之间相互作用的动力学。对于从事前沿研究的化学家来说，使用最先进的NMR光谱仪是必不可少的。这些NMR研究的结果将对有机金属合成、天然产物化学、生物化学、重金属络合和物理有机化学产生影响。