Acquisition of a 700 MHz Cryoprobe NMR

采集 700 MHz 冷冻探针 NMR

• 批准号: 0421356
• 负责人: Andrew Maverick
• 金额: --
• 依托单位: Louisiana State University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-08-01 至 2007-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0421356&HistoricalAwards=false
• 关键词: Acquisition; 700; MHz; Cryoprobe; NMR

With support from the Major Research Instrumentation (MRI) Program, Luigi G. Marzilli, Robert P. Hammer and George G. Stanley, of the Department of Chemistry at Louisiana State University and A&M College will acquire a 700 MHz NMR spectrometer equipped with advanced cryoprobe probe technology. The equipment includes a superconducting 700 MHz magnet system with 5.4 cm bore (field at 16.43 Tesla), and a triple resonance inverse cryoprobe with filters, cooled preamplifiers for proton and deuterium-lock, and actively shielded Z-gradient. This instrument will enable the following research projects: a) studies of Metal-DNA interactions; b) bioanalytical separations using chiral polymers; c) beta-Sheet propensity of alpha, alpha-disubstituted amino acids; d) aggregation & association of porphyrin sensitizers; e) NMR studies of tetrapyrrole systems; f) molecular level investigations of pollutant & membrane interactions with natural organic matter; and g) in situ NMR studies of a bimetallic catalyst. Faculty at a number of area institutions (Southern University, Grambling, Dillard and Xavier) will also have access to the 700MHz instrument. Nuclear Magnetic Resonance (NMR) spectroscopy is one of the most powerful tools available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectrometers is essential to chemists who are carrying out frontier research. The results from these NMR studies will have an impact in environmental chemistry and biochemistry.

在主要研究仪器（MRI）计划的支持下，Luigi G.作者声明：Robert P. Hammer，乔治G.路易斯安那州立大学和A M学院化学系的斯坦利将获得一台配备先进冷冻探针技术的700 MHz核磁共振光谱仪。 该设备包括一个超导700 MHz的磁体系统与5.4厘米的孔（场在16.43特斯拉），和一个三重共振反向冷冻探针与过滤器，冷却质子和氘锁前置放大器，并积极屏蔽Z梯度。 该仪器将使以下研究项目成为可能：a）金属-DNA相互作用的研究; B）使用手性聚合物的生物分析分离; c）α，α-二取代氨基酸的β-折叠倾向; d）卟啉敏化剂的聚集缔合; e）四吡咯系统的NMR研究; f）污染物膜与天然有机物相互作用的分子水平研究;以及g）催化剂的原位NMR研究。 一些地区机构（南方大学、Grambling、Dillard和Xavier）的教师也将获得700 MHz仪器。 核磁共振（NMR）光谱是化学家用来阐明分子结构的最有力的工具之一。它用于识别未知物质，表征分子内原子的特定排列，并研究溶液中分子之间相互作用的动力学。对于从事前沿研究的化学家来说，使用最先进的NMR光谱仪是必不可少的。这些NMR研究的结果将对环境化学和生物化学产生影响。