A New Design for Manufacturing Process of Porous Resorbable Implant Materials
多孔可吸收植入材料制造工艺的新设计
基本信息
- 批准号:0440215
- 负责人:
- 金额:--
- 依托单位:
- 依托单位国家:美国
- 项目类别:Standard Grant
- 财政年份:2004
- 资助国家:美国
- 起止时间:2004-08-15 至 2005-01-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
The objective of this research is to explore the possibility of manufacturing resorbable implant material from powder phase via fiber stage to porous scaffold. The envisioned manufacturing process will consider in particular the mixture with collagen for extra tensile strength and toughness of implant materials. The approach is to adapt some of the key manufacturing process in the paper-making industry for a more efficient and economic production of biocompatible open cell porous implant materials. The important manufacturing concepts include both wet and dry end operations as well as an additional ceramic hydroxyapatite fiber convertion process. In the wet end operation, hydroxyapatite and collagen fibers will be mixed with chemical additives and distributed uniformly to a moving wire mat. In the dry end operation, implant material sheets will be transported through a serious of drying apparatus and fit into different sized sheets or rolls.The societal benefits of this proposed research include the potentially feasible mass production of implant materials with open cell porous microstructures mimicking the nature. The branching out of the paper manufacturing techniques in the production of advanced biocompatible implant materials is beneficial not only to the paper industry per se but also to the emerging bioscience and bioengineering industrial sectors. The educational impacts include fostering multi-disciplinary engineering education in the Othmer Interdisciplinary Research Institute in Polytechnic University, an institute in the Metropolitan New York area focusing the education of students with different religious and ethnic backgrounds.
本研究的目的是探索从粉末相到纤维相再到多孔支架的可吸收植入材料的可能性。设想的制造工艺将特别考虑与胶原蛋白的混合物,以获得植入物材料的额外拉伸强度和韧性。该方法是为了适应造纸工业中的一些关键制造工艺,以更有效和经济地生产生物相容性开孔多孔植入材料。重要的制造概念包括湿端和干端操作以及额外的陶瓷羟基磷灰石纤维转化过程。在湿部操作中,羟基磷灰石和胶原纤维将与化学添加剂混合并均匀地分布到移动的丝网垫上。在干燥端操作中,植入材料片将通过一系列干燥设备输送并适合于不同尺寸的片或卷。这项拟议研究的社会效益包括具有模仿自然的开孔多孔微结构的植入材料的潜在可行的大规模生产。 在生产先进的生物相容性植入材料中,造纸技术的分支不仅有利于造纸工业本身,而且有利于新兴的生物科学和生物工程工业部门。教育方面的影响包括在理工大学的Othmer跨学科研究所促进多学科工程教育,该研究所是纽约大都会地区的一个研究所,重点是教育具有不同宗教和族裔背景的学生。
项目成果
期刊论文数量(0)
专著数量(0)
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Sheldon Wang其他文献
Arden-Based Clinical Decision Support in an Object-Oriented World
面向对象世界中基于 Arden 的临床决策支持
- DOI:
- 发表时间:
1996 - 期刊:
- 影响因子:0
- 作者:
R. Corman;Joyce T. Sager;Jiang Wu;Sheldon Wang;D. N. Daine;Dave McEwan - 通讯作者:
Dave McEwan
On Explicit / Implicit and Incompressible / Compressible Issues of Immersed Boundary / Continuum Methods
关于浸没边界/连续体方法的显式/隐式和不可压缩/可压缩问题
- DOI:
- 发表时间:
2008 - 期刊:
- 影响因子:0
- 作者:
Xiaodong;Sheldon Wang - 通讯作者:
Sheldon Wang
CLIPS: The C language integrated production system
CLIPS:C语言集成制作系统
- DOI:
- 发表时间:
1994 - 期刊:
- 影响因子:0
- 作者:
R. Corman;Joyce T. Sager;Jiang Wu;Sheldon Wang;D. N. Daine;Dave McEwan - 通讯作者:
Dave McEwan
A Simplified Model for the Study of Film-Boiling Droplet Motion on Microscale Ratchets
研究微型棘轮上薄膜沸腾液滴运动的简化模型
- DOI:
- 发表时间:
2024 - 期刊:
- 影响因子:0
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Sheldon Wang;J. T. Ok;Sunggook Park;Mahmoud Elsharafi;Yu Guo - 通讯作者:
Yu Guo
On Leakage Issues of Sucker Rod Pumping Systems
有杆抽油系统泄漏问题探讨
- DOI:
- 发表时间:
2019 - 期刊:
- 影响因子:0
- 作者:
Sheldon Wang;Lynn Rowlan;M. Elsharafi;Mansur Ermila;Tomas Grejtak;Ca Taylor - 通讯作者:
Ca Taylor
Sheldon Wang的其他文献
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{{ truncateString('Sheldon Wang', 18)}}的其他基金
SGER: Multi-Scale and Multi-Physics Modeling of Normal and Sickle Red Blood Cells in Aqueous Environment
SGER:水环境中正常红细胞和镰状红细胞的多尺度和多物理场建模
- 批准号:
0503649 - 财政年份:2004
- 资助金额:
-- - 项目类别:
Standard Grant
A New Design for Manufacturing Process of Porous Resorbable Implant Materials
多孔可吸收植入材料制造工艺的新设计
- 批准号:
0503652 - 财政年份:2004
- 资助金额:
-- - 项目类别:
Standard Grant
SGER: Multi-Scale and Multi-Physics Modeling of Normal and Sickle Red Blood Cells in Aqueous Environment
SGER:水环境中正常红细胞和镰状红细胞的多尺度和多物理场建模
- 批准号:
0406601 - 财政年份:2004
- 资助金额:
-- - 项目类别:
Standard Grant
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