Modernization of the Biology Curriculum through Adaptation of an Investigative Laboratory in Molecular Biology

通过分子生物学研究实验室的改造实现生物学课程的现代化

• 批准号: 0511375
• 负责人: Margaret Kovach
• 金额: $ 8.56万
• 依托单位: University of Tennessee Chattanooga
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-09-01 至 2008-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0511375&HistoricalAwards=false
• 关键词: Modernization; Biology; Curriculum; through; Adaptation

Discipline: Biological Sciences (61)The University of Tennessee at Chattanooga is updating its biology offerings through development of an integrative, collaborative and inquiry-based course of study in Molecular Biology.Intellectual Merit: To answer the growing need for biologists skilled in the areas of molecular and cell biology, genetics, biotechnology, molecular medicine and bioinformatics generated by increased interest by industry and academia in human and non-human genome studies and to address current and future needs in the education of undergraduates in biology, current course offerings in Genetics and Molecular Biology (MB) are being enhanced and modernized. Practices being introduced in course design include hands-on exposure to advanced and widely applicable benchtop techniques in biotechnology and the use of scientific and literature databases and molecular biology analysis software. Specific components being introduced reflect adaptation of investigative laboratory curriculum materials originally developed by the Genome Consortium for Active Teaching (GCAT) at Davidson College for their advanced molecular biology course and include: (1) incorporation of laboratory exercises utilizing the green fluorescent protein, and (2) acquisition of basic and advanced biotechnological instrumentation.Broader Impacts: This expansion of the curriculum extends faculty development and student growth through interdisciplinary and cross-disciplinary interactions as well as impacts individual student research projects. The revised molecular biology course has wide application by including experiences in the genetic manipulation and molecular characterization of both prokaryotic and eukaryotic systems and incorporating technologies intended to facilitate student/faculty research and development in general biology, genetics, microbiology, cell biology, biochemistry and bioinformatics. The changes instituted involve faculty from both the departments of Computer Science and Chemistry in the development of cross-disciplinary courses, such as Bioinformatics, within the Biology Department and incorporation of molecular biology techniques and analyses into courses and accepted courses for the major within the other departments. Emphasis is being placed on investigative learning exercises that include a progression of scientific experiences with opportunities for data analysis, interpretation, written expression and oral presentation of results.

田纳西大学查塔努加分校（University of Tennessee at Chattanooga）正在通过开发一门综合性、合作性和探究性的分子生物学课程来更新其生物学课程。智力优势：由于工业界和学术界对人类和非人类基因组研究的兴趣日益浓厚，对分子和细胞生物学、遗传学、生物技术、分子医学和生物信息学领域的生物学家的需求日益增长，为了满足生物学本科生教育的当前和未来需求，遗传学和分子生物学（MB）目前的课程设置正在得到加强和现代化。课程设计中引入的实践包括亲身接触生物技术中先进和广泛适用的台式技术，以及使用科学和文献数据库以及分子生物学分析软件。引入的特定组件反映了戴维森学院主动教学基因组联盟（GCAT）最初为其高级分子生物学课程开发的调查实验室课程材料的适应性，包括：(1)结合利用绿色荧光蛋白的实验室练习，以及(2)获得基本和先进的生物技术仪器。更广泛的影响：课程的扩展通过跨学科和跨学科的互动扩展了教师的发展和学生的成长，并影响了学生的个人研究项目。修订后的分子生物学课程具有广泛的应用，包括原核和真核系统的遗传操作和分子表征方面的经验，并结合旨在促进学生/教师在普通生物学、遗传学、微生物学、细胞生物学、生物化学和生物信息学方面的研究和发展的技术。这些变化涉及到计算机科学系和化学系的教师在生物学系内开发跨学科课程，如生物信息学，并将分子生物学技术和分析纳入其他系的课程和接受的专业课程中。目前的重点是调查性学习练习，其中包括科学经验的发展，并有机会进行数据分析、解释、书面表达和口头陈述结果。