Acquisition of a Fluorescence Imaging System for Research in Biology, Environmental Science and Chemistry at UT Chattanooga

购买荧光成像系统用于 UT 查塔努加分校的生物学、环境科学和化学研究

• 批准号: 0320715
• 负责人: Margaret Kovach
• 金额: --
• 依托单位: University of Tennessee Chattanooga
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-08-01 至 2006-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0320715&HistoricalAwards=false
• 关键词: Acquisition; Fluorescence; Imaging; System; Research

A grant has been awarded to the University of Tennessee at Chattanooga under the direction of Dr. Margaret Kovach for the acquisition of a fluorescent imaging system that will be used as an important research and teaching tool for the Departments of Biological and Environmental Sciences and Chemistry. The Departments of Biological and Environmental Sciences and Chemistry have a strong tenet for involving undergraduate students in research and, since the inception of the masters program, graduate students as well.The requested instrumentation is necessary for performing molecular analysis and detection and can be used for a wide range of applications including genotyping, differential display, mutation detection, and forensics. The system will also be compatible with a wide variety of gel, membrane, microplate (ELISA) and microarray-based technologies used for analyzing DNA, RNA and protein samples. The research projects in genomics and proteomics, toxicology and biochemistry that will be supported by access to this instrumentation are associated with the laboratories and research interests of the five P.I.s . For example, the fluorescence imaging system will support studies of gene regulation through comparative analyses of gene expression profiles, the comparative study of microbial populations, the study of toxicological effects at the level of DNA and protein, and mutation detection and analysis by chemically induced mutagenesis.The acquisition of this imaging system will allow students and professors from both departments to increase the number and variety of experimental procedures available to conduct research. In addition, shared access to the fluorescent imaging system will enhance interdisciplinary courses, curricula and research between the departments. More than any other single item of equipment, the fluorescence imaging system will allow UTC to develop and sustain vigorous research and teaching programs that employ genomic and proteomic approaches to benefit current research programs in molecular biology, microbiology, toxicology and biochemistry.

在玛格丽特·科瓦奇博士的指导下，田纳西大学查塔努加分校获得了一笔赠款，用于购买荧光成像系统，该系统将用作生物和环境科学系以及化学系的重要研究和教学工具。生物与环境科学系和化学系有一个很强的宗旨，让本科生参与研究，自硕士课程开始以来，研究生也参与研究。所需的仪器是进行分子分析和检测所必需的，可用于广泛的应用，包括基因分型，差异显示，突变检测和法医学。该系统还将与用于分析DNA、RNA和蛋白质样品的各种凝胶、膜、微孔板（ELISA）和基于微阵列的技术兼容。在基因组学和蛋白质组学，毒理学和生物化学的研究项目，将通过访问该仪器的支持与实验室和五个PI的研究兴趣。例如，荧光成像系统将通过基因表达谱的比较分析、微生物种群的比较研究、在DNA和蛋白质水平上的毒理学效应研究，和突变检测和化学诱变分析。这一成像系统的收购将使学生和教授从两个部门，以增加数量和品种，可用于进行研究的实验程序。此外，共享荧光成像系统将加强各部门之间的跨学科课程，课程和研究。荧光成像系统比任何其他单一设备都更能帮助UTC开发和维持强有力的研究和教学计划，这些计划采用基因组学和蛋白质组学方法，使当前的分子生物学、微生物学、毒理学和生物化学研究计划受益。