MRI: Acquisition of an NMR Spectrometer to Support Undergraduate Research and Curriculum Reform

MRI：购置核磁共振波谱仪以支持本科生研究和课程改革

• 批准号: 0521077
• 负责人: Scott Ulrich
• 金额: $ 25.72万
• 依托单位: Ithaca College
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-08-15 至 2008-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0521077&HistoricalAwards=false
• 关键词: MRI; Acquisition; NMR; Spectrometer; Support

With support from the Major Research Instrumentation (MRI) Program, the Department of Chemistry at Ithaca College will acquire a 300 MHz nuclear magnetic resonance (NMR) Spectrometer. This equipment will enable researchers to carry out studies on a) the synthesis and characterization of stable, electron-deficient divalent silicon species; b) kinetic and mechanistic studies of proton transfer between oxygen and carbon; c) antibacterial drug discovery; d) development of Ruthenium-based olefin polymerization/small molecule activation catalysts; and e) the synthesis of dendrimers used in tissue engineering studies. Nuclear Magnetic Resonance (NMR) spectroscopy is one of the most powerful tools available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectrometers is essential to chemists who are carrying out frontier research. The results from these NMR studies will have an impact in medicinal chemistry, biotechnology and polymer synthesis.

在主要研究仪器（MRI）计划的支持下，伊萨卡学院化学系将获得一台300兆赫的核磁共振（NMR）光谱仪。该设备将使研究人员能够进行以下研究：a)稳定的缺电子二价硅的合成和表征；B)氧与碳之间质子转移的动力学和机理研究；C)抗菌药物发现；d)钌基烯烃聚合/小分子活化催化剂的开发；e)用于组织工程研究的树状大分子的合成。核磁共振（NMR）波谱是化学家用来研究分子结构的最有力的工具之一。它用于识别未知物质，表征分子内原子的特定排列，以及研究溶液中分子之间相互作用的动力学。获得最先进的核磁共振光谱仪是必不可少的化学家谁正在进行前沿研究。这些核磁共振研究的结果将对药物化学、生物技术和聚合物合成产生影响。