MRI: Acquisition of an NMR Console, Probe, and Autosampler to Advance Undergraduate Research and Education

MRI：购买 NMR 控制台、探头和自动进样器以推进本科生研究和教育

• 批准号: 2215171
• 负责人: Scott Ulrich
• 金额: $ 25万
• 依托单位: Ithaca College
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-08-15 至 2025-07-31
• 项目状态: 未结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2215171&HistoricalAwards=false
• 关键词: MRI; Acquisition; NMR; Console; Probe

This award is jointly supported by the Major Research Instrumentation and the Chemistry Research Instrumentation Programs. Ithaca College is acquiring an upgraded console and probe for a 400 MHz NMR spectrometer to support the research of Professor Scott Ulrich and colleagues Michael P. Haaf and Anna Larsen. This instrument facilitates research in the areas of polymer science, inorganic chemistry, and medicinal chemistry. In general, Nuclear Magnetic Resonance (NMR) spectroscopy is one of the most powerful tools available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution or in the solid state. Access to state-of-the-art NMR spectrometers is essential to chemists who are carrying out frontier research. This instrument enhances the educational, research, and teaching efforts of students at all levels in the Chemistry Department at Ithaca College as well as provides accessibility for use at nearby institutions. This instrument enables increased diverse representation of undergraduate and high school students through established outreach programs.The award of the 400 MHz NMR spectrometer upgrade is aimed at enhancing undergraduate research and education at all levels, especially in areas such as polymer, organometallic, and medicinal chemistry. The instrument impacts research focused on discovering polymers of intrinsic microporosity, and on the characterization of chiral lactide polymer catalysts. Other investigations include the synthesis of iridium and rhodium pincer complexes and medicinal chemistry targeting bacterial signaling enzymes and cancer cell metabolism.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

该奖项由主要研究仪器项目和化学研究仪器项目共同支持。伊萨卡学院正在为400 MHz核磁共振光谱仪购买升级的控制台和探测器，以支持斯科特·乌尔里希教授及其同事迈克尔·P·哈夫和安娜·拉森的研究。该仪器促进了聚合物科学、无机化学和药物化学领域的研究。总的来说，核磁共振波谱是化学家用来阐明分子结构的最强大的工具之一。它被用来识别未知物质，表征分子中原子的特定排列，并研究分子在溶液或固体中相互作用的动力学。对于正在进行前沿研究的化学家来说，获得最先进的核磁共振光谱仪是必不可少的。该仪器加强了伊萨卡学院化学系各级学生的教育、研究和教学努力，并为附近机构的使用提供了便利。该仪器通过已建立的推广计划，增加了本科生和高中生的多样化代表性。400 MHz核磁共振光谱仪升级的获奖旨在加强所有级别的本科生研究和教育，特别是在聚合物、有机金属和药物化学等领域。该仪器影响的研究重点是发现具有固有微孔率的聚合物，以及手性丙交酯聚合物催化剂的表征。其他的研究工作包括合成铱和铑的钳形化合物，以及针对细菌信号酶和癌细胞代谢的药物化学。这一奖项反映了NSF的法定使命，并通过使用基金会的智力优势和更广泛的影响审查标准进行评估，被认为值得支持。

项目成果

Distinct modes of Si–H binding to Rh in complexes of a phosphine-diarylamido-silane (SiNP) pincer ligand

膦-二芳基酰胺-硅烷 (SiNP) 钳配体复合物中 Si–H 与 Rh 结合的不同模式

• DOI: 10.1039/d2dt02175g
• 发表时间: 2022
• 期刊: Dalton Transactions
• 影响因子: 4
• 作者: Rain Talosig, A.;Cosio, Mario N.;Morse, Benjamin;Nguyen, Vinh T.;Kosanovich, Alex J.;Pell, Christopher J.;Li, Chun;Bhuvanesh, Nattamai;Zhou, Jia;Larsen, Anna S.
• 通讯作者: Larsen, Anna S.