Nanoscale Dynamic Analysis of Surface Properties of Biopolymers

生物聚合物表面性质的纳米级动态分析

• 批准号: 0528506
• 负责人: Kyriakos Komvopoulos
• 金额: $ 25万
• 依托单位: University of California-Berkeley
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-08-01 至 2008-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0528506&HistoricalAwards=false
• 关键词: Nanoscale; Dynamic; Analysis; Surface; Properties

Nanoscale Dynamic Analysis of Surface Properties of BiopolymersGrand CMS-0528506AbstractThe longevity of joint implants and the efficiency of catheterizationtechniques greatly depend on fundamental understanding of the dynamicsurface properties of polymers used in these applications. The motivationof this research is to bridge the gap of knowledge of the dynamic responseof biopolymer surfaces. The research consists of the following main tasks:(a) gamma-irradiation and plasma-assisted surface modification ofmedical-grade polyethylenes, (b) characterization of the surface topographyand chemical behavior of the treated polymers, and (c) investigation of thedynamic behavior of both unmodified and treated polymers using dynamicforce microprobe analysis. The significance of this research is the basicinsight into nanoscale surface phenomena of biopolymers with directimplications in biomedical applications.

生物聚合物表面性质的纳米级动态分析Grand CMS-0528506摘要关节植入物的寿命和导管插入技术的效率在很大程度上取决于对这些应用中使用的聚合物的动态表面性质的基本理解。本研究的动机是弥合生物聚合物表面动态响应知识的差距。本论文的主要工作包括：（a）医用聚乙烯的γ-辐照和等离子体辅助表面改性，（B）改性后聚合物表面形貌和化学行为的表征，（c）用动态力微探针研究改性前后聚合物的动态行为。本研究的意义在于对生物高分子纳米表面现象的基本认识，并在生物医学应用中具有直接的应用价值。