Food quality effetcs on parasite-host interactions

食品质量对寄生虫与宿主相互作用的影响

• 批准号: 174794510
• 负责人: Professor Dr. Dominik Martin-Creuzburg
• 金额: --
• 依托单位: Evolutionsbiologie
• 依托单位国家: 德国
• 项目类别: Research Grants
• 财政年份: 2010
• 资助国家: 德国
• 起止时间: 2009-12-31 至 2013-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/174794510?language=en
• 关键词: Food; quality; effetcs; parasite; host

The availability of essential resources may significantly affect parasite–host interactions. A low availability of essential dietary resources may impair the fitness of the host thereby increasing its susceptibility to pathogenic infections (reduced immune defences). Alternatively, a low dietary provisioning with essential resources may impair the fitness of host and parasite, because resource–limited hosts may provide less resources for the parasite (competition). The objective of this project is to assess how the availability of essential lipids (polyunsaturated fatty acids, sterols) affects interactions between the host Daphnia magna and its bacterial and microsporidian parasites. For this purpose, life history experiments will be conducted with infected and uninfected D. magna feeding on lipid deficient algae supplemented with single fatty acids or sterols. Effects of food quality on host performance will be assessed by comparing fitness parameters of infected and uninfected hosts; effects of food quality on parasite performance will be assessed by determining the efficiency and intensity of infection. Results obtained in this project will contribute to our understanding of the timing of epidemics, associated consequences for population dynamics, and the evolution of parasite–host systems.

重要资源的可用性可能会显着影响寄生虫与宿主的相互作用。基本饮食资源的缺乏可能会损害宿主的健康，从而增加其对病原体感染的易感性（免疫防御能力降低）。另外，必需资源的低饮食供应可能会损害宿主和寄生虫的健康，因为资源有限的宿主可能为寄生虫提供较少的资源（竞争）。该项目的目的是评估必需脂质（多不饱和脂肪酸、甾醇）的可用性如何影响宿主大型溞与其细菌和微孢子虫寄生虫之间的相互作用。为此，将对感染和未感染的 D. magna 进行生活史实验，这些 D. magna 以补充有单一脂肪酸或甾醇的脂质缺乏藻类为食。将通过比较感染和未感染宿主的健康参数来评估食品质量对宿主性能的影响；将通过确定感染的效率和强度来评估食品质量对寄生虫性能的影响。该项目获得的结果将有助于我们了解流行病发生的时间、种群动态的相关后果以及寄生虫-宿主系统的进化。

项目成果

The potential of dietary polyunsaturated fatty acids to modulate eicosanoid synthesis and reproduction in Daphnia magna: a gene expression approach.

• DOI: 10.1016/j.cbpa.2012.05.004
• 发表时间: 2012-08
• 期刊: Comparative biochemistry and physiology. Part A, Molecular & integrative physiology
• 作者: Nina Schlotz;J. G. Sørensen;D. Martin‐Creuzburg

A dietary polyunsaturated fatty acid improves consumer performance during challenge with an opportunistic bacterial pathogen.

膳食多不饱和脂肪酸可提高消费者在机会性细菌病原体挑战期间的表现

• DOI: 10.1111/1574-6941.12407
• 发表时间: 2014
• 期刊: FEMS microbiology ecology
• 影响因子: 4.2
• 作者: Schlotz;Pester;Freese;Martin-Creuzburg
• 通讯作者: Martin-Creuzburg