Nonlinear Chemical Dynamics

非线性化学动力学

• 批准号: 0615507
• 负责人: Irving Epstein
• 金额: $ 80.5万
• 依托单位: Brandeis University
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-01 至 2010-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0615507&HistoricalAwards=false
• 关键词: Nonlinear; Chemical; Dynamics

Irving R. Epstein and Anatol Zhabotinsky of Brandeis University are supported by an award from the Theoretical and Computational Chemistry program for research in nonlinear chemical dynamics. The award is supported with partial co-funding by the Division of Mathematical Sciences and the Office of International Science and Engineering at NSF. The PIs are designing new chemical oscillators using commercially available enzymes and substrates and are using these systems for pattern engineering. The studies employ both experimental and computational techniques. They are also doing research to construct the first pH oscillators that will operate under batch conditions. This research is being carried out in collaboration with investigators in Hungary. The expectation is that these reactions might be useful in the development of drug delivery systems and molecular motors or sensors. A collaborative study involving scientists in the United Kingdom in which magnetic resonance imaging will be used to explore three-dimensional patterns in a reaction diffusion micro-emulsion system (the BZ-AOT system) developed in the PI's laboratory. The study will, in addition, probe the effects of coupling between patterns in different layers in several oscillating chemical reactions. Finally, the PIs are studying the effects on pattern formation of cross-diffusion, a phenomenon in which the movement of one species through space is influenced by gradients in the concentrations of other species. The latter study involves a collaboration with scientists in Italy in which experiments using the European Synchrotron Radiation Facility will be used to investigate and compare the detailed structures in the BZ-AOT system with a phospholipid system. The work is having a broad impact on our understanding of pattern formation in chemical systems and a further broad impact through the involvement of students in international research.

欧文河布兰迪斯大学的Epstein和Anatol Zhabotinsky获得了理论和计算化学计划的非线性化学动力学研究奖。 该奖项由数学科学部和NSF国际科学与工程办公室共同资助。 PI正在设计新的化学振荡器，使用商业上可用的酶和底物，并使用这些系统的模式工程。 这些研究采用了实验和计算技术。 他们还在研究建造第一个在批量条件下运行的pH振荡器。 这项研究是与匈牙利的调查人员合作进行的。 期望这些反应可能在药物递送系统和分子马达或传感器的开发中有用。 一项涉及英国科学家的合作研究，其中磁共振成像将用于探索PI实验室开发的反应扩散微乳液系统（BZ-AOT系统）中的三维模式。 此外，该研究还将探讨几种振荡化学反应中不同层图案之间的耦合效应。 最后，研究所正在研究交叉扩散对格局形成的影响，交叉扩散是一种物质在空间中的移动受到其他物质浓度梯度影响的现象。 后一项研究涉及与意大利科学家的合作，其中将使用欧洲同步加速器辐射设施进行实验，以调查和比较BZ-AOT系统与磷脂系统的详细结构。 这项工作对我们理解化学系统中的模式形成产生了广泛的影响，并通过学生参与国际研究产生了进一步的广泛影响。