LTREB: A Long-Term Study of Host-Parasite Interactions

LTREB：宿主-寄生虫相互作用的长期研究

• 批准号: 0640639
• 负责人: Curtis Lively
• 金额: $ 42.49万
• 依托单位: Indiana University
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-03-15 至 2013-02-28
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0640639&HistoricalAwards=false
• 关键词: LTREB; Long; Term; Study; Host

Intellectual merit. The long-term maintenance of genetic diversity in natural populations is widely regarded as one of the most interesting challenges for biologists. The parasite hypothesis predicts that parasites and pathogens will evolve to infect common host genotypes disproportionately, thereby resulting in the long-term maintenance of genetic variation. The parasite hypothesis will be tested using long-term surveys in conjunction with a series of laboratory infection experiments focused on a diverse population of freshwater snails and their parasitic worms. The results will be of broad interest to ecologists, parasitologists, and conservation geneticists. Broader impacts. This study system has brought together an international group of scientists and students. As in the past, these investigators will continue to train undergraduates in the basic ideas surrounding host-parasite coevolution and the maintenance of genetic variation; every effort will be made to attract undergraduate students from under-represented groups and to give them hands on experience in research. Previous results from this system have been used in textbooks, television shows, and radio programs. Because the basic ideas surrounding host-parasite coevolution are generally very accessible, they are nicely suited for educational purposes. They also have important ramifications for conservation biology, agricultural practices, and disease ecology.

智力上的优点。 自然种群遗传多样性的长期维持被广泛认为是生物学家最感兴趣的挑战之一。 寄生虫假说预测寄生虫和病原体将进化成不成比例地感染共同的宿主基因型，从而导致遗传变异的长期维持。 寄生虫假说将使用长期调查结合一系列实验室感染实验，重点是不同的淡水蜗牛及其寄生蠕虫的人口进行测试。 这些结果将引起生态学家、寄生虫学家和保护遗传学家的广泛兴趣。 更广泛的影响。 该研究系统汇集了一批国际科学家和学生。 与过去一样，这些研究人员将继续对本科生进行围绕宿主-寄生虫共同进化和遗传变异维持的基本思想培训;将尽一切努力吸引来自代表性不足群体的本科生，并为他们提供研究经验。 该系统的先前结果已用于教科书、电视节目和广播节目。 因为宿主-寄生虫共同进化的基本思想通常很容易理解，所以它们非常适合教育目的。 它们对保护生物学、农业实践和疾病生态学也有重要的影响。