MRI: Acquisition of a High-Resolution Scanning Electron Microscope for an Interdisciplinary, Multi-User Facility Serving Life, Physical, and Materials Sciences

威斯康星大学密尔沃基分校（UWM）化学系将从主要研究仪器（MRI）项目中获得一台高分辨率扫描电子显微镜（SEM）。该仪器将用于细胞表面和纳米粒子共轭物的高分辨率成像，研究新的表面和纳米结构，研究复合材料和胶体，开发先进的纳米电子和自旋电子材料，以及纳米探针的制造和表征。高分辨率扫描电子显微镜是许多研究领域（化学、物理、材料、工程、生物等）的重要表征工具。扫描电子显微镜使用聚焦电子束扫描样品表面。这提供了纳米尺度上的图像和结构。在材料科学中，高分辨率合成成像对于开发具有新功能的纳米材料至关重要。在生物学领域，这种能力允许纳米颗粒附着在细胞表面的定位，以识别受体和其他蛋白质，回答有关细胞表面功能位点分布的问题。电子显微镜技术将用于研究生的研究和教学。新的扫描电镜操作的便利性将使许多课程包括电子显微镜的经验成为可能。远程操作能力将用于加强UWM和密尔沃基公立学校系统之间的现有联系，通过与UWM职前教师开发基于高水平探究的实验。

The Chemistry Department at the University of Wisconsin Milwaukee (UWM) will acquire a high resolution scanning electron microscope (SEM) with this award from the Major Research Instrumentation (MRI) program. This instrument will be used in the high resolution imaging of cell surfaces and nanoparticle conjugates, investigating novel surfaces and nanostructures, the study of composites & colloids, the development of advanced nano-electronic and spintronic materials and in nanoprobe fabrication & characterization.High resolution scanning electron microscopy is a critical characterization tool in many research areas (chemistry, physics, materials, engineering, biology, etc.). SEM uses a focused electron beam to scan the surface of a sample. This provides images and structures on a nanometer scale. In materials science, high resolution compositional imaging is crucially important for the development of nanomaterials with novel functionality. In the biological area, this capability allows for the localization of nanoparticles attached to cell surfaces for the identification of receptors and other proteins, answering questions about the distribution of functional sites on the surface of cells. Electron microscopy technology will be used in graduate student research and instruction. The ease of operation of the new SEM will make it feasible for many courses to include an electron microscopy experience. The remote operation capabilities will be used to strengthen the existing links between UWM and the Milwaukee Public School system by developing high-level inquiry based experiments with UWM pre-service teachers.