Molecular mechanisms underlying cross-talk phenomena in hormone-regulated plant defense responses in Arabidopsis thaliana

拟南芥激素调节植物防御反应中串扰现象的分子机制

• 批准号: 186359484
• 负责人: Professorin Dr. Christiane Gatz
• 金额: --
• 依托单位: Abteilung Molekularbiologie und Physiologie der Pflanze
• 依托单位国家: 德国
• 项目类别: Research Grants
• 财政年份: 2010
• 资助国家: 德国
• 起止时间: 2009-12-31 至 2014-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/186359484?language=en
• 关键词: Molecular; mechanisms; underlying; cross; talk

Plants live in complex environments in which they have to combat a broad range of microbial pathogens. Under this selective pressure, plants have developed a highly sophisticated defense system that recognizes pathogen-associated molecules. Subsequently, appropriate defense responses are activated many of them being coordinated by the phytohormones salicylic acid (SA), jasmonic acid (JA) and ethylene (ET). While infection with biotrophic pathogens evokes SA-mediated defense responses, infection with necrotrophic pathogens elicits JA/ET-dependent responses. Both signaling pathways cross-communicate in an antagonistic manner, so that defense pathways can be prioritized upon demand. Here we aim to elucidate the molecular mechanisms underlying this cross-talk. Recently, we have presented genetic evidence that TGA transcription factors, which have been classified as essential activators of SA-mediated responses, are also required for the activation of JA- and ET-dependent defense mechanisms in Arabidopsis thaliana. This activation function seems to be negatively regulated by SA. This proposal aims to understand cross-talk mechanisms between the SA and the ET defense hormone pathways.

植物生活在复杂的环境中，它们必须与广泛的微生物病原体作斗争。在这种选择压力下，植物已经发展出一种高度复杂的防御系统，可以识别病原体相关分子。随后，适当的防御反应被激活，其中许多由植物激素水杨酸（SA），茉莉酸（JA）和乙烯（ET）协调。活体营养型病原体感染引起SA介导的防御反应，而坏死营养型病原体感染引起JA/ET依赖性反应。两种信号通路以对抗的方式交叉通信，因此可以根据需求优先考虑防御通路。在这里，我们的目标是阐明这种串扰的分子机制。最近，我们已经提出了遗传证据表明，TGA转录因子，这已被归类为SA介导的反应的必要激活剂，也需要在拟南芥JA和ET依赖的防御机制的激活。这种激活功能似乎是负调控SA。该提案旨在了解SA和ET防御激素通路之间的串扰机制。

项目成果

TGA Transcription Factors Activate the Salicylic Acid-Suppressible Branch of the Ethylene-Induced Defense Program by Regulating ORA59 Expression1[C][W]

• DOI: 10.1104/pp.114.243360
• 发表时间: 2014-07
• 期刊: Plant Physiology
• 影响因子: 7.4
• 作者: Mark Zander;Corinna Thurow;C. Gatz