MRI: Acquisition of a 400 MHz NMR Spectrometer to Enhance Undergraduate Research and Research Training at Willamette University

MRI：购买 400 MHz NMR 波谱仪以加强威拉米特大学本科生研究和研究培训

• 批准号: 0821781
• 负责人: Andrew Duncan
• 金额: $ 40.98万
• 依托单位: Willamette University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-08-01 至 2011-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0821781&HistoricalAwards=false
• 关键词: MRI; Acquisition; 400; MHz; NMR

With this award from the Major Research Instrumentation program (MRI), Andrew Duncan and colleagues Sarah Kirk and Joseph Williamson from Willamette University will acquire a 400 MHz Nuclear Magnetic Resonance (NMR) spectrometer. The proposed research spans the disciplines of organic, bioorganic, physical, and organometallic chemistry. Some examples are the synthesis and characterization of neomycin/amino acid and tetracaine/cGMP conjugates and studies of the mechanism of ene-allene ring closing metathesis reactions.Nuclear Magnetic Resonance spectroscopy is one of the most powerful tools available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectrometers is essential to chemists who are carrying out frontier research. The results from these NMR studies will have an impact in synthetic organic/inorganic chemistry and biochemistry. This award will also contribute to the advancement of women in science.

通过主要研究仪器项目（MRI）的奖励，来自威拉米特大学的Andrew Duncan和他的同事Sarah Kirk和Joseph Williamson将获得一台400 MHz核磁共振（NMR）光谱仪。提议的研究跨越有机、生物有机、物理和有机金属化学等学科。例如新霉素/氨基酸和丁卡因/cGMP偶联物的合成和表征以及烯-烯合环复合反应机理的研究。核磁共振波谱学是化学家用来阐明分子结构的最有力的工具之一。它用于识别未知物质，表征分子内原子的特定排列，以及研究溶液中分子之间相互作用的动力学。获得最先进的核磁共振光谱仪是必不可少的化学家谁正在进行前沿研究。这些核磁共振研究的结果将对合成有机/无机化学和生物化学产生影响。该奖项还将为女性在科学领域的进步做出贡献。