NSEC on Molecular Function at the Nano/Bio Interface

NSEC 探讨纳米/生物界面的分子功能

• 批准号: 0832802
• 负责人: Alan Johnson
• 金额: $ 1150万
• 依托单位: University of Pennsylvania
• 依托单位国家: 美国
• 项目类别: Cooperative Agreement
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-01 至 2015-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0832802&HistoricalAwards=false
• 关键词: NSEC; Molecular; Function; Nano; Bio

The Nanoscale Science and Engineering Center (NSEC) at the University of Pennsylvania, the Nano/Bio Interface Center (NBIC), designs and controls molecular functionality, quantifies behavior of individual molecules and interactions at organic/inorganic interfaces to establish the foundation for understanding the interface of physical and biological systems. The NSEC unites investigators from five schools (the School of Engineering and Applied Science, the School of Medicine, the School of Arts and Sciences, Wharton Business School, and the Graduate School of Education) to provide, not only new directions for the life sciences but also for engineering, in a two-way flow essential to fully realizing the benefits of the intersection of biology with nanotechnology. A comprehensive program uses fundamental research enterprises as a platform for curriculum development, pre-college educational programs, out reach to the community, and commercialization.Two multi disciplinary research teams are focused on: optoelectronic function in synthetic biomolecules and mechanical motion of molecules from physiological systems. In each area physical interfaces probe, control, or influence the outcome. A cross-cutting initiative brings together investigators who develop nanoscale measurement tools to produce the next wave of innovation in probes of molecular function and enables research in both teams. To enable these advances the NBIC has established the Nano/Bio Probe Facility. The Nano/Bio Probe Innovation Facility assembles a comprehensive set of enabling research tools to support research interactions that would otherwise be difficult or impossible to sustain. The Facility is unique to Penn, where the newest advances in probing single molecule and nanostructure behavior are made available to the research community. The facility opened in 2005 and now has over 80 users. The NBIC established and leads a large portfolio of educational programs. An undergraduate minor in Nanotechnology now serves 70 students from 3 schools and with representation from all engineering departments. The graduate certificate in Nanotechnology has an enrolment of 20 students. An annual summer high school academy offers a residential program on Nanotechnology that obtains enrollment of ~25 students/year. A strong theme of NBIC outreach addresses professional development of pre-college teachers in the Philadelphia region. A highlight is the Research Experiences for Teachers (RET) program that is a collaboration with Drexel University. A partnership with Alabama State University has established programs to impact the pipeline of future scientists and engineers. A variety of community outreach activities are highlighted at the annual NanoDay@Penn.

宾夕法尼亚大学的纳米科学与工程中心（NSEC），纳米/生物界面中心（NBIC），设计和控制分子功能，量化单个分子的行为和有机/无机界面的相互作用，为理解物理和生物系统的界面奠定基础。 NSEC联合来自五所学校（工程与应用科学学院，医学院，艺术与科学学院，沃顿商学院和教育研究生院）的调查人员，不仅为生命科学提供新的方向，而且为工程提供双向流动，这对充分实现生物学与纳米技术交叉的好处至关重要。 一个综合性的计划使用基础研究企业作为平台，课程开发，大学预科教育计划，接触社区，和商业化。两个多学科的研究团队专注于：合成生物分子的光电功能和生理系统分子的机械运动。 在每一个领域中，物理接口都在探测、控制或影响结果。 一项跨领域的计划汇集了开发纳米级测量工具的研究人员，以产生分子功能探针的下一波创新，并使两个团队的研究成为可能。为了实现这些进步，NBIC建立了纳米/生物探针设施。 Nano/Bio Probe Innovation Facility汇集了一套全面的研究工具，以支持否则难以或不可能维持的研究互动。该设施是宾夕法尼亚大学独有的，在那里探测单分子和纳米结构行为的最新进展可供研究界使用。 该设施于2005年启用，目前有80多个用户。 NBIC建立并领导了大量的教育项目。 纳米技术的本科未成年人现在为来自3所学校的70名学生提供服务，并代表所有工程部门。 在纳米技术研究生证书有20名学生入学。 一年一度的夏季高中学院提供了一个关于纳米技术的住宿计划，每年招收约25名学生。 NBIC外展活动的一个重要主题是费城地区大学预科教师的专业发展。 其中一个亮点是与德雷克塞尔大学合作的教师研究经验（RET）计划。 与亚拉巴马州立大学的合作伙伴关系已经建立了影响未来科学家和工程师管道的计划。 在一年一度的NanoDay@Penn上突出了各种社区外展活动。