FASEB Summer Research Conference: Circumventricular Organs to be held Saxtons River, VT; July 17-22, 1993

约翰逊·格罗斯9224876大脑受到相对不透气的血脑屏障的保护，血脑屏障是由围绕大脑毛细血管的神经胶质细胞诱导的。但在这一障碍中存在差距。脑室壁中特殊分化的器官--脑室周围器官--含有神经元，神经元上有多种血液传播的化学物质的受体。这些神经元形成早期预警网络，维持大脑和身体的动态平衡。它们是自主神经和神经内分泌系统功能的有影响力的调节者。这些器官中的一些已被证明在调节血压方面至关重要，但到目前为止，人们还不知道新发现的多肽神经递质的作用，也不知道这些器官如何作为一个系统一起发挥作用。这笔NSF拨款将允许八名年轻科学家参加由实验生物学联合会组织的夏季脑室周围器官研究会议。这次会议的目的是将基础和临床科学家聚集在一起，交换信息，并促进对这一研究领域潜在重要性的更好理解。***

Johnson Gross 9224876 The brain is protected from contact with the environment by a relatively impermeable blood-brain barrier induced by the neuroglial cells that surround brain capillaries. But there are gaps in this barrier. Specially differentiated organs -- circumventricular organs -- in the ventricular walls contain neurons with receptors for a variety of blood-borne chemicals. These neurons form early warning networks that maintains brain and body homeostasis. They are influential regulators of autonomic and neuroendocrine system functions. Some of these organs have shown to be crucially important in the regulation of blood pressure but there is as yet no understanding of the role of the newly discovered peptide neurotransmitters or how the organs function together as a system. This NSF grant will allow eight young scientists to participate in a summer research conference on the circumventricular organs organized by the Federated Societies of Experimental Biology. The purpose of this conference is to bring basic and clinical scientists together to exchange information and to foster a greater understanding of the potential importance of this area of research. ***