AIR Option 2: Research Alliance Bio-enabled Nanosensors with Fully Programmable Ligand Detection

AIR 选项 2：具有完全可编程配体检测功能的研究联盟生物纳米传感器

• 批准号: 1312202
• 负责人: Alan Johnson
• 金额: $ 80万
• 依托单位: University of Pennsylvania
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-05-01 至 2016-04-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1312202&HistoricalAwards=false
• 关键词: AIR; Option; Research; Alliance; Bio

This PFI: AIR Research Alliance project focuses on the translation and transfer of programmable, nano-enabled chemical sensor technologies to fill technology gaps in medical diagnostics and environmental monitoring. The technologies have the following market-valued features: programmable ligand sensitivity, miniature form factor, and compatibility with lab-on-a-chip technology, that provide exemplary sensitivity, selectivity, and overall performance when compared to the leading competing technologies in this market domain, for example ELISA tests and metal oxide gas sensors. The project accomplishes this transfer to the market by developing a set of platform technologies suitable for incorporation into commercial products across a broad set of applications, resulting in creation of new jobs in sensor systems design and manufacturing, commercial products for analysis of disease biomarkers and air/water quality, with the potential to license intellectual property generated by the project that will result in spinoffs. The partners engaged to transfer the technologies to the market domain include major industry (Intel, Lockheed Martin), start up ventures (Adamant Technologies, Graphene Frontiers), and a technology-based economic development program (Ben Franklin Technology Partners of Southeastern Pennsylvania) with a network of angel investors. The partners will provide crucial insight into potential markets and application spaces, as well as access to critical technical capabilities and capital that will enable the new ventures that emerge to flourish. The potential economic impact is expected to be on the scale of tens to hundreds of millions of dollars in the next five to ten years, which will contribute to the U.S. competitiveness in this global chemical sensors market. The societal impact in the short term will be the creation of technologies that will drive a transformation to a "smart society" where integrated chemical sensor systems are ubiquitous. The longer term impacts include a new generation of science and engineering students, educated in depth in their discipline but also with experience in the agile, dynamic thinking processes that are characteristic of innovative, entrepreneurial small businesses.

该PFI：AIR研究联盟项目的重点是可编程的纳米化学传感器技术的翻译和转让，以填补医疗诊断和环境监测方面的技术空白。 这些技术具有以下市场价值的功能：可编程配体灵敏度，微型形状因子以及与芯片实验室技术的兼容性，与该市场领域的领先竞争技术（例如ELISA测试和金属氧化物气体传感器）相比，这些技术提供了示例性的灵敏度，选择性和整体性能。 该项目通过开发一套适用于广泛应用的商业产品的平台技术来实现向市场的转移，从而在传感器系统设计和制造、用于分析疾病生物标志物和空气/水质量的商业产品方面创造新的就业机会，并有可能许可该项目产生的知识产权，从而产生副产品。 参与将技术转移到市场领域的合作伙伴包括主要行业（英特尔，洛克希德马丁公司），初创企业（金刚石技术，石墨烯前沿）和一个基于技术的经济发展计划（宾夕法尼亚州东南部的本富兰克林技术合作伙伴），以及天使投资者网络。 合作伙伴将提供对潜在市场和应用空间的重要见解，以及获得关键技术能力和资本的机会，使新出现的企业蓬勃发展。在未来五到十年内，潜在的经济影响预计将达到数千万到数亿美元的规模，这将有助于美国在全球化学传感器市场的竞争力。 短期内的社会影响将是技术的创造，这些技术将推动向“智能社会”的转变，在智能社会中，集成化学传感器系统无处不在。长期的影响包括新一代的科学和工程专业的学生，在他们的学科深入教育，但也有经验的敏捷，动态的思维过程是创新，创业型小企业的特点。