Upgrade of a 300 MHz NMR Spectrometer for Research and Teaching

升级 300 MHz NMR 波谱仪用于研究和教学

• 批准号: 0840523
• 负责人: Martin Kirk
• 金额: $ 29.84万
• 依托单位: University of New Mexico
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-08-01 至 2012-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0840523&HistoricalAwards=false
• 关键词: Upgrade; 300; MHz; NMR; Spectrometer

This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).With support from the Chemistry Research Instrumentation and Facilities:Multiuser program (CRIF:MU), the Department of Chemistry and Chemical Biology at the University of New Mexico will upgrade the console of a 300 MHz nuclear magnetic resonance spectrometer that will be used for solids and solution analyses. It will be employed in research projects that span many areas of chemistry including, a) the development of reliable protocols for the assessment of structure and bonding in high-spin Co(II) systems; b) the discovery of new catalytic reactions and efficient assembly of diverse and medicinally important chemical structures; c) investigation of Donor-Bridge-Acceptor systems as potential components of molecular wire devices; d) development of novel synthetic methods for biomedically interesting targets; e) understanding the mechanism of carbon dioxide reacting with main group amides to generate organic isocyanates; f) characterization of early stage molecular precursor chemistry for the development of new families of "doped" materials that become novel gas adsorbents, once converted to solid-state forms; g) strategies for the rational design of inhibitors for enzymes connected to diseases; h) characterization of carbon fibers used in cathodes of high power microwave sources with potential military applications; and i) characterization of bacterial communities in cave pools and their role in formation of caverns.Multinuclear NMR spectroscopy is an essential tool in modern chemical research. NMR spectra enable researchers to identify reaction products including targeted substances, reaction intermediates and unexpected products. Structural information, i.e. information on the connectivity of the atoms in molecules and materials is obtained by detecting transitions between energy levels arising from the nuclear spin properties of atoms. The instruments will be used to support research projects of undergraduates, graduate students, and postdoctoral researchers, including traditionally underrepresented minority groups that make up approximately half of the enrollment at the university.

该奖项是根据2009年美国复苏和再投资法案（公法111-5）资助的。在化学研究仪器和设施：多用户计划（CRIF：MU）的支持下，新墨西哥州大学化学和化学生物学系将升级300 MHz核磁共振光谱仪的控制台，该光谱仪将用于固体和溶液分析。 它将用于跨越许多化学领域的研究项目，包括：a）开发用于评估高自旋Co（II）系统中结构和键合的可靠协议; B）发现新的催化反应和有效组装不同和医学上重要的化学结构; c）研究作为分子线器件潜在组件的供体-桥-受体系统; e）了解二氧化碳与主族酰胺反应生成有机异氰酸酯的机理; f）表征早期分子前体化学，用于开发新的“掺杂”材料家族，这些材料一旦转化为固态形式就成为新型气体吸附剂; g）合理设计与疾病有关的酶的抑制剂的策略; h）表征具有潜在军事应用的高功率微波源阴极中使用的碳纤维; i）表征洞穴池中的细菌群落及其在洞穴形成中的作用。多核NMR光谱是现代化学研究中的重要工具。 NMR光谱使研究人员能够识别反应产物，包括目标物质，反应中间体和意外产物。 结构信息，即关于分子和材料中原子的连接性的信息，通过检测由原子的核自旋性质引起的能级之间的跃迁来获得。 这些工具将用于支持本科生，研究生和博士后研究人员的研究项目，包括传统上代表性不足的少数群体，占大学入学人数的一半左右。