Cold Spring Harbor Laboratory Advanced Bacterial Genetics Course

冷泉港实验室高级细菌遗传学课程

• 批准号: 0919304
• 负责人: Terri Grodzicker
• 金额: $ 46.66万
• 依托单位: Cold Spring Harbor Laboratory
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-07-01 至 2014-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0919304&HistoricalAwards=false
• 关键词: Cold; Spring; Harbor; Laboratory; Advanced

In this project, Cold Spring Harbor Laboratory will continue its highly successful postgraduate laboratory short course in Advanced Bacterial Genetics. This intensive and heavily over-subscribed course has a long pedigree of advanced training in cutting-edge, modern microbial genetics, with its roots in a laboratory course started by Nobel laureate Max Delbruck in 1945. The three-week summer course prepares each participant to enter directly into research that makes use of advanced techniques and concepts in the molecular genetics of bacterial systems. Because the course experiments address real research questions, in addition to exposing students to different techniques, they provide training in experimental design, trouble-shooting and real data analysis. Daily discussion periods cover the methodology, experimental design and analysis and invited speakers introduce students to diverse areas of modern microbial research. The course stimulates interaction among new investigators with diverse backgrounds and interest and provides training towards research in modern microbiology.Broader ImpactTraining scientists in the latest techniques in bacterial genetics is important for our greater understanding of many living systems, since bacteria are omnipresent in our environment and essential to human life, at times representing significant or potential threats in terms of infectious diseases, environmental imbalance and even bioterrorism. Each year, this course trains a new generation of young scientists in state-of-the-art techniques in how to probe the inner workings of bacteria, and how to use this understanding in a variety of applications in biotechnology and agriculture. Given the relative simplicity of the bacterial cell compared to that of multicellular organisms, scientists are now attempting to model the entire system of the cell, using a combination of genetics and computer modeling to understand the fundamental operation system of these organisms. The course provides fertile ground for students and faculty to meet and discuss the intricacies of the science in a relaxed but intensive environment, which many subsequently cite as some of the most significant and formative of their scientific careers, enabling collaboration and interactions that are maintained and strengthened for years into the future.

在这个项目中，冷泉港实验室将继续其非常成功的研究生实验室短期课程，在先进的细菌遗传学。这个密集和严重超额认购的课程在尖端的现代微生物遗传学方面有着悠久的高级培训血统，其根源在于诺贝尔奖获得者Max Delbruck于1945年开始的实验室课程。为期三周的夏季课程准备每个参与者直接进入研究，利用先进的技术和概念，在细菌系统的分子遗传学。 由于课程实验解决真实的研究问题，除了让学生接触不同的技术，他们提供实验设计，故障排除和真实的数据分析的培训。每天的讨论时间涵盖方法，实验设计和分析，特邀演讲者向学生介绍现代微生物研究的各个领域。本课程鼓励具有不同背景和兴趣的新研究人员之间的互动，并提供现代微生物学研究的培训。更广泛的影响培养科学家了解细菌遗传学的最新技术对我们更好地了解许多生命系统非常重要，因为细菌在我们的环境中无处不在，对人类生命至关重要，有时会对传染病构成重大或潜在的威胁，环境失衡甚至生物恐怖主义。 每年，这门课程培训新一代的年轻科学家在国家的最先进的技术，在如何探测细菌的内部运作，以及如何使用这种理解在生物技术和农业的各种应用。鉴于细菌细胞与多细胞生物相比相对简单，科学家们现在正试图对细胞的整个系统进行建模，使用遗传学和计算机建模的结合来了解这些生物的基本操作系统。该课程为学生和教师提供了肥沃的土壤，让他们在轻松但密集的环境中会面并讨论科学的复杂性，许多人随后将其引用为他们科学生涯中最重要和最具影响力的部分，从而使合作和互动能够在未来几年保持和加强。