Conference: 2005 CSHL Eukaryotic mRNA Processing Conference, August 24 -28, 2005

会议：2005 CSHL 真核 mRNA 加工会议，2005 年 8 月 24 日至 28 日

• 批准号: 0516649
• 负责人: Terri Grodzicker
• 金额: $ 0.5万
• 依托单位: Cold Spring Harbor Laboratory
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-08-01 至 2006-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0516649&HistoricalAwards=false
• 关键词: Conference; 2005; CSHL; Eukaryotic; mRNA

The Cold Spring Harbor Laboratory Eukaryotic mRNA Processing Conference will be held August 24-28, 2005 at Cold Spring Harbor Laboratory in New York. This conference, the fifth in a biennial series, will focus on various aspects of mRNA processing, transport, RNA interference, informatics and turn-over. Major advances have recently been made in these areas, and the conference will be a timely event for discussing the latest unpublished results and exchanging ideas, thereby fostering new developments in this rapidly moving field. A major focus will be on nuclear events in mRNA maturation, particularly mRNA splicing and polyadenylation, but the scope has been expanded to encompass both the impact of the history of an mRNA on its ultimate biological fate, the emerging fields of RNA interference and microRNA function as well as the application of informatics to the analysis of RNA processing. The meeting format will consist of eight plenary sessions and three poster sessions. Speakers in the plenary sessions will be selected on the basis of the submitted abstracts, which will encourage active participation by junior scientists. The main topics covered will include: catalytic mechanisms of mRNA splicing and 3'-end processing; developmental and cell-type specific regulation of gene expression by alternative splicing and polyadenylation; structure and function of snRNP and hnRNP particles; mechanisms of RNA interference and microRNA function; assembly of processing machineries; mRNA transport, decay and localization; and integration of processing with transcription and translation.

冷泉港实验室真核mRNA加工会议将于2005年8月24-28日在纽约的冷泉港实验室举行。 本次会议是两年一次的系列会议中的第五次，将重点关注mRNA加工，运输，RNA干扰，信息学和周转的各个方面。最近在这些领域取得了重大进展，这次会议将是一个及时的事件，讨论最新的未发表的结果和交流思想，从而促进这一迅速发展的领域的新发展。 一个主要的重点将是核事件在mRNA成熟，特别是mRNA剪接和多聚腺苷酸化，但范围已扩大到包括mRNA的历史对它的最终生物命运的影响，RNA干扰和microRNA功能的新兴领域，以及信息学的应用分析RNA加工。会议形式将包括八次全体会议和三次海报会议。将根据提交的摘要挑选全体会议的发言者，这将鼓励年轻科学家积极参与。所涵盖的主要议题将包括：mRNA剪接和3 '端加工的催化机制;通过选择性剪接和多聚腺苷酸化对基因表达的发育和细胞类型特异性调节; snRNP和hnRNP颗粒的结构和功能; RNA干扰和microRNA功能的机制;加工机器的组装; mRNA运输，衰变和定位;以及加工与转录和翻译的整合。