MRI: Acquisition of a 400 MHz NMR Spectrometer to Support Undergraduate Research and Research Training at Lawrence University and the Fox Valley Region of Wisconsin

有了这项来自重大研究仪器（MRI）计划的奖项，Stefan Debbert和同事大卫霍尔，来自劳伦斯大学的罗恩佩克和来自威斯康星州-狐狸谷大学的马丁路德将获得一台400 MHz NMR光谱仪，以支持包括设计新型分子支架，开发有机金属-多胺缀合物，以及设计新的金属-有机框架材料和二吡啉-金属络合物在内的研究。 此外，生物化学和生物学教师将使用该仪器进行病毒肽和盐生盐杆菌生物合成调节的结构活性研究。 研究人员在U。威斯康星州-狐狸谷将利用该光谱仪开展含硒和碲阴离子的研究。 两个校区的学生也可以在他们的课程中使用仪器。核磁共振（NMR）光谱是化学家用来阐明分子结构的最强大的工具之一。它用于识别未知物质，表征分子内原子的特定排列，并研究溶液中分子之间相互作用的动力学。对于从事前沿研究的化学家来说，使用最先进的NMR光谱仪是必不可少的。这些NMR研究的结果将对合成有机/无机化学和生物化学产生影响。该仪器将成为教学和研究的一个组成部分。

With this award from the Major Research Instrumentation (MRI) program, Stefan Debbert and colleagues David Hall, and Ron Peck from Lawrence University and Martin Rudd from the University of Wisconsin - Fox Valley will acquire a 400 MHz NMR spectrometer to support research that includes designing novel molecular scaffolds, developing organometallic-polyamine conjugates, and designing new metal-organic framework materials and dipyrrin-metal complexes. In addition, biochemistry and biology faculty will use the instrument to conduct structure-activity studies of viral peptides and of biosynthetic regulation in Halobacterium salinarium. Researchers at U. Wisconsin - Fox Valley will use the spectrometer to carry out studies of selenium - and tellurium - containing anions. Students at both campuses will have access to the instrumentation in their coursework as well.Nuclear Magnetic Resonance (NMR) spectroscopy is one of the most powerful tools available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectrometers is essential to chemists who are carrying out frontier research. The results from these NMR studies will have an impact in synthetic organic/inorganic chemistry and biochemistry. This instrument will be an integral part of teaching as well as research.