MRI: Acquisition of a 400 MHz NMR Spectrometer to Support Undergraduate Research and Research Training at Lawrence University and the Fox Valley Region of Wisconsin

获得重大研究仪器(MRI)计划的这一奖项后，来自劳伦斯大学的Stefan Debbert及其同事David Hall、来自劳伦斯大学的Ron Peck和来自威斯康星大学福克斯谷分校的Martin Rudd将获得一台400 MHz核磁共振谱仪，以支持包括设计新型分子支架、开发金属有机-多胺结合物、以及设计新的金属-有机骨架材料和联吡咯-金属配合物的研究。此外，生物化学和生物学系将使用该仪器进行病毒多肽的结构-活性研究和盐生杆菌的生物合成调节。威斯康星大学福克斯谷分校的研究人员将使用该光谱仪对含硒和含碲的阴离子进行研究。这两个校区的学生也可以在他们的课程中使用这些仪器。核磁共振光谱学是化学家可以用来阐明分子结构的最强大的工具之一。它被用来识别未知物质，表征分子内原子的特定排列，并研究溶液中分子之间相互作用的动力学。对于正在进行前沿研究的化学家来说，获得最先进的核磁共振光谱仪是必不可少的。这些核磁共振研究的结果将对合成有机/无机化学和生物化学产生影响。该仪器将成为教学和研究不可或缺的一部分。

With this award from the Major Research Instrumentation (MRI) program, Stefan Debbert and colleagues David Hall, and Ron Peck from Lawrence University and Martin Rudd from the University of Wisconsin - Fox Valley will acquire a 400 MHz NMR spectrometer to support research that includes designing novel molecular scaffolds, developing organometallic-polyamine conjugates, and designing new metal-organic framework materials and dipyrrin-metal complexes. In addition, biochemistry and biology faculty will use the instrument to conduct structure-activity studies of viral peptides and of biosynthetic regulation in Halobacterium salinarium. Researchers at U. Wisconsin - Fox Valley will use the spectrometer to carry out studies of selenium - and tellurium - containing anions. Students at both campuses will have access to the instrumentation in their coursework as well.Nuclear Magnetic Resonance (NMR) spectroscopy is one of the most powerful tools available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectrometers is essential to chemists who are carrying out frontier research. The results from these NMR studies will have an impact in synthetic organic/inorganic chemistry and biochemistry. This instrument will be an integral part of teaching as well as research.