Nanofabrication Using Viral Biotemplates for MEMS Applications

使用病毒生物模板进行 MEMS 应用的纳米加工

• 批准号: 0927693
• 负责人: Reza Ghodssi
• 金额: $ 40.17万
• 依托单位: University of Maryland, College Park
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-07-15 至 2013-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0927693&HistoricalAwards=false
• 关键词: Nanofabrication; Using; Viral; Biotemplates; MEMS

The objective of this work is to utilize the self-assembly and metal-binding properties of a biological nanostructure, the Tobacco mosaic virus (TMV), in the development of novel functional materials and fabrication processes for small-scale energy microsystems applications. The TMV is a high aspect ratio cylindrical plant virus that can be genetically engineered to include amino acids with enhanced metal-binding properties. These genetic modifications facilitate electroless plating of the molecules as well as self-assembly onto various substrates. Particular emphasis will be placed on integrating the TMV biofabrication into standard micromachining through the combination of bottom-up and top-down approaches such as DNA-directed patterning, molecular self-assembly, photolithography and thin-film deposition. The developed processes will be readily incorporated in the fabrication of nanostructured small-scale energy storage devices. The outcome of this proposal will result in the realization of novel strategies for nanomanufacturing that alleviate several limitations currently involved in the integration of nanostructures into microsystems fabrication. The envisioned results are not limited only in the field of energy, but can be used by researchers to develop other types of devices where nanomaterials can mark a significant improvement, such as sensors with high selectivity and sensitivity and miniaturized heat dissipation components that can be integrated with commercial electronic products. The wide range of scientific matters involved in this investigation provides an ideal interdisciplinary "training matrix" for students from diverse backgrounds interested in research and education careers by bringing together aspects of science and engineering previously distinct from one another.

这项工作的目的是利用生物纳米结构，烟草花叶病毒（TMV）的自组装和金属结合特性，在小规模能源微系统应用的新型功能材料和制造工艺的发展。TMV是一种高长径比的圆柱形植物病毒，其可以被遗传工程改造以包括具有增强的金属结合特性的氨基酸。这些基因修饰促进了分子的化学镀以及在各种基底上的自组装。特别强调的是将TMV生物织物集成到标准的微加工通过自下而上和自上而下的方法，如DNA定向图案化，分子自组装，光刻和薄膜沉积的组合。 开发的过程将很容易纳入纳米结构的小规模储能装置的制造。这一建议的结果将导致实现纳米制造的新策略，减轻目前涉及的几个限制，在集成的纳米结构到微系统制造。设想的结果不仅限于能源领域，而且可以被研究人员用于开发其他类型的设备，其中纳米材料可以标志着显着的改进，例如具有高选择性和灵敏度的传感器以及可以与商业电子产品集成的小型化散热组件。在这项调查中涉及的广泛的科学问题提供了一个理想的跨学科的“培训矩阵”，为学生从不同的背景感兴趣的研究和教育事业，汇集了科学和工程方面以前彼此不同。