Fundamental Study of Carbon Dots for Fluorescence Bio-imaging/sensing

用于荧光生物成像/传感的碳点的基础研究

• 批准号: 0967423
• 负责人: Ya-Ping Sun
• 金额: $ 33.3万
• 依托单位: Clemson University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-07-01 至 2015-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0967423&HistoricalAwards=false
• 关键词: Fundamental; Study; Carbon; Dots; Fluorescence

0967423SunThe proposed project is to carry out a fundamental study of carbon as a new element for quantum dot-like fluorescent nanomaterials. Recently, the PI?s group found and reported that small carbon nanoparticles could be surface-passivated to exhibit strong fluorescence in the visible and nearinfrared spectral regions. The focus of the proposed project will be on the further exploration and development, both fundamentally and technologically, of these fluorescent carbon nanoparticles (dubbed ?carbon dots?). While the original discovery of carbon dots was driven largely by carbon being obviously non-toxic, subsequent studies have revealed their many superb characteristics, including their being highly competitive in fluorescence performance. There are very good reasons to expect that with further development the carbon dots technology will play a significant role in advanced optical imaging and sensing for biomedical and human health related applications. In addition, an understanding of the fact that nanoscale carbon exhibits semiconductor-like optical properties should contribute to the fundamental knowledge on materials at the nanoscale, which may inspire the discovery of new concepts and new materials.

本项目拟开展碳作为量子点荧光纳米材料新元素的基础研究。最近，PI？S组发现并报道了小碳纳米颗粒可以表面钝化，在可见光和近红外光谱区表现出强烈的荧光。拟议项目的重点将是进一步探索和开发这些荧光碳纳米颗粒(被称为？碳点?)。虽然碳点的最初发现主要是由于碳具有明显的无毒特性，但随后的研究揭示了它们的许多极好的特性，包括它们在荧光性能方面具有很强的竞争力。我们有充分的理由期待，随着碳点技术的进一步发展，它将在生物医学和人类健康相关应用的先进光学成像和传感方面发挥重要作用。此外，了解纳米级碳具有类似半导体的光学性质，将有助于了解纳米级材料的基本知识，这可能会激发新概念和新材料的发现。