Collaborative Research: Guided Electrowetting for Agile Channel Formation in Reconfigurable Lab-on-a-Chip

合作研究:引导电润湿在可重构芯片实验室中实现敏捷通道形成

基本信息

  • 批准号:
    1001146
  • 负责人:
  • 金额:
    $ 16万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
    Standard Grant
  • 财政年份:
    2010
  • 资助国家:
    美国
  • 起止时间:
    2010-07-01 至 2014-06-30
  • 项目状态:
    已结题

项目摘要

The objective of this research is to collaboratively create an integrated and hybrid lab-on-chip platform that is electronically configured on-demand and maintains its programmed configuration without electrical power. A single chip can access a vast library of microfluidic functions. The approach is balancing 3-D electrowetting and Young-Laplace forces, such that emergent control in microchannel formation and fluid transport can be realized. The intellectual merit is that new scientific models will be developed for electrofluidics. A simple graphical programming of lab-on-chip will be created, and the fields of continuous channel microfluidics and digital electrowetting transport will be united. Furthermore, the lab-on-chip community will be able to leverage the enormous infrastructure for liquid crystal display manufacturing and 4-bit computer interfacing, to deploy highly affordable and agile lab-on-chip products for rapid chemical and biological discovery. Broader impacts include integration of this project with NSF sponsored microfluidics course development, inspiring undergraduates to pursue advanced STEM degrees through the University of Cincinnati?s research co-op program, and continued involvement with NSF REU and RET programs. The significance of this proposed project stems from the need for lab-on-chip to full-fill promises to broadly reduce health-care costs, and provide remote access to patient diagnostics or environmental testing. For example, clinics could perform diagnostic tests such as immunoassays and nucleic acid assays with little laboratory support. Such agile lab-on-chip modules would allow user-defined access to laboratory tasks, all contained in a portable module that could have ergonomics as simple as an i-Phone.(243 words)
本研究的目标是合作创建一个集成和混合的芯片实验室平台,该平台可以按需进行电子配置,并在没有电力的情况下保持其编程配置。单个芯片可以访问大量的微流控函数库。该方法平衡了三维电润湿力和杨-拉普拉斯力,从而实现了对微通道形成和流体输运的紧急控制。智力上的优点是将为电流体学开发新的科学模型。将建立一个简单的图形化的芯片实验室编程,并将连续通道微流体和数字电润湿输运领域结合起来。此外,芯片实验室社区将能够利用液晶显示器制造和4位计算机接口的庞大基础设施,部署价格合理且灵活的芯片实验室产品,用于快速的化学和生物发现。更广泛的影响包括该项目与美国国家科学基金会赞助的微流体课程开发的整合,激励本科生通过辛辛那提大学攻读高级STEM学位。并继续参与NSF REU和RET项目。这一拟议项目的意义在于,芯片实验室需要全面履行广泛降低医疗保健成本的承诺,并提供远程病人诊断或环境测试。例如,诊所可以在几乎没有实验室支持的情况下进行免疫测定和核酸测定等诊断测试。这种灵活的芯片实验室模块将允许用户自定义访问实验室任务,所有这些都包含在便携式模块中,其人体工程学设计就像iphone一样简单。(243字)

项目成果

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Philip Rack其他文献

Low-Temperature Charging Dynamics of the Ionic Liquid and Its Gating Effect on FeSe0.5Te0.5 Superconducting Films
离子液体的低温充电动力学及其对FeSe0.5Te0.5超导薄膜的门控效应
  • DOI:
    10.1021/acsami.9b02373
  • 发表时间:
    2019
  • 期刊:
  • 影响因子:
    9.5
  • 作者:
    Cheng Zhang;Wei Zhao;Sheng Bi;Christopher Rouleau;Jason Fowlkes;Walker Boldman;Genda Gu;Qiang Li;Guang Feng;Philip Rack
  • 通讯作者:
    Philip Rack
Adding Solvent into Ionic Liquid-Gated Transistor: The Anatomy of Enhanced Gating Performance
在离子液体门控晶体管中添加溶剂:增强门控性能的剖析
  • DOI:
    10.1021/acsami.9b03433
  • 发表时间:
    2019
  • 期刊:
  • 影响因子:
    9.5
  • 作者:
    Wei Zhao;Sheng Bi;Cheng Zhang;Philip Rack;Guang Feng
  • 通讯作者:
    Guang Feng

Philip Rack的其他文献

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{{ truncateString('Philip Rack', 18)}}的其他基金

OP: Collaborative Research: Nanoscale Synthesis, Characterization and Modeling of Rationally Designed Plasmonic Materials and Architectures
OP:合作研究:合理设计的等离子体材料和结构的纳米级合成、表征和建模
  • 批准号:
    1709275
  • 财政年份:
    2017
  • 资助金额:
    $ 16万
  • 项目类别:
    Standard Grant
Collaborative Research: Computations, Modeling and Experiments of Self and Directed Assembly for Nanoscale Liquid Metal Systems
合作研究:纳米级液态金属系统自组装和定向组装的计算、建模和实验
  • 批准号:
    1603780
  • 财政年份:
    2016
  • 资助金额:
    $ 16万
  • 项目类别:
    Standard Grant
CPS: Synergy: Collaborative Research: Cyber-physical digital microfluidics based on active matrix electrowetting technology: software-programmable high-density pixel arrays
CPS:协同:协作研究:基于有源矩阵电润湿技术的网络物理数字微流体:软件可编程高密度像素阵列
  • 批准号:
    1544686
  • 财政年份:
    2015
  • 资助金额:
    $ 16万
  • 项目类别:
    Standard Grant
Collaborative Research: Experimental and Computational Study of the Instabilities, Transport, and Self Assembly of Nanoscale Metallic Thin Films and Nanostructures
合作研究:纳米级金属薄膜和纳米结构的不稳定性、输运和自组装的实验和计算研究
  • 批准号:
    1235651
  • 财政年份:
    2012
  • 资助金额:
    $ 16万
  • 项目类别:
    Continuing Grant
Collaborative Research: Electrofluidic Carbon Nanofiber Arrays for Multi-Dimensional Separations
合作研究:用于多维分离的电流体碳纳米纤维阵列
  • 批准号:
    0728860
  • 财政年份:
    2007
  • 资助金额:
    $ 16万
  • 项目类别:
    Standard Grant
NER: Nanoscale Electron Beam Stimulated Processing
NER:纳米级电子束刺激处理
  • 批准号:
    0210339
  • 财政年份:
    2002
  • 资助金额:
    $ 16万
  • 项目类别:
    Standard Grant

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