Summer Undergraduate Research in Chemistry and Biochemistry at Miami University

这项由化学系(CHE)和生物基础设施部(DBI)颁发的奖项支持由迈阿密大学(俄亥俄州)Christopher A.Makaroff领导的本科生研究体验(REU)网站，从2010年开始，为期三个夏天。该网站将在为期十周的计划中，每年夏天为十名学生提供支持。这些研究项目侧重于化学和生物学跨学科领域的合作研究。样本项目包括：(1)新近发现的将完全折叠的蛋白质输送到类囊体腔的系统；(2)用于分离化学物种的聚合物柱的开发；(3)生物活性天然产物的合成；(4)在活体条件下单宁的命运的阐明；(5)对光和/或化学刺激的响应的可重构表面的合成和研究；(6)蓝藻异胞分化的研究；(7)用核磁共振方法研究完整膜蛋白的结构和动力学；(8)研究在减数分裂和有丝分裂过程中参与染色体凝聚和姐妹染色单体凝聚的蛋白质；(9)设计和开发有效测量学生学习的工具。除了在研究活跃的机构接触尖端研究外，参加该项目的学生还将参加实地考察、专业发展活动和道德培训。被招募到拟议地点的学生将来自没有重大研究机会的学校，以及学生人数众多、化学专业代表性不足的学校。年轻科学家需要接触现代研究方法和工具，作为他们培训的一部分。这个REU网站旨在为相当数量的学生提供实际的、动手的研究培训，这些学生在他们的母校可能没有这个机会。学生们在迈阿密大学(俄亥俄州)期间将从事的跨学科项目是跨学科工作的极好例子，这种工作正变得越来越典型，成为现代实验室研究最富有成效的途径。在这个网站参与研究的学生将为进入研究生院做好准备，并最终成为国家技术劳动力的一部分。

This award from the Division of Chemistry (CHE) and the Division of Biological Infrastructure (DBI) supports a Research Experience for Undergraduates (REU) site led by Christopher A. Makaroff at Miami University (Ohio) for three summers, commencing in 2010. The site will support ten students per summer in a ten week program. The research projects focus on collaborative research in interdisciplinary areas of chemistry and biology. Sample projects include: (1) the recently-discovered system that transports fully-folded proteins into the thylakoid lumen; (2) the development of polymeric columns for separations of chemical species; (3) the synthesis of biologically-active natural products; (4) the elucidation of the fate of tannin under in vivo conditions; (5) the synthesis and study of reconfigurable surfaces, responsive to light and/or chemical stimuli; (6) the study of heterocyst differentiation in cyanobacteria; (7) the study of the structure and dynamics of integral membrane proteins with NMR methods; (8) the study of proteins involved in chromosome condensation and sister chromatid cohesion during meiosis and mitosis; (9) the design and development of tools to effectively measure student learning . Besides being exposed to cutting-edge research at a research-active institution, the students participating in this program will participate in site visits, professional development activities, and ethical training. Students targeted for the recruitment to the proposed site will come from schools without significant opportunities for research as well as schools with large populations of students underrepresented in chemistry.Young scientists need exposure to modern research methods and tools as part of their training. This REU site aims to provide practical, hands-on research training to a significant number of students who might not have this opportunity at their home institution. The interdisciplinary projects that the students will work on while at Miami University (Ohio) are excellent examples of the kinds of cross-disciplinary work that is becoming more and more typical of the most fruitful avenues for modern laboratory research. Students participating in research at this site will be well-prepared for graduate school, and eventual employment as part of the country's technical workforce.