Cognitive Rhythms Collaborative: A Discovery Network

该基金支持波士顿地区的一组科学家合作节律合作组织（CRC），他们开始共同努力推进我们对认知功能（如注意力、感觉、运动计划和记忆）背后的大脑动力学的理解。越来越多的人认为，动力学是理解大脑如何工作的核心，但在我们所知道的和我们如何寻求了解更多方面存在重大差距。CRC关注的是与认知最密切相关的动力机制，频率范围为1 - 200 Hz的节律性活动。其中心目标是描述这些节律的生理起源和功能，并了解节律动力学中的病理如何与神经系统疾病的症状和机制相关。数学建模，尖端的统计技术，以及它们作为计算机算法的实现将是执行其科学计划的关键。该基金将支持CRC，重点关注数学科学在脑动力学研究中的应用，以及由具有挑战性的科学问题驱动的新数学、统计和计算技术的潜力。这将包括对技术核心的支持，该技术核心将创建新的硬件/软件平台来支持这些技术。该中心还将为大批学生和博士后提供指导和教学。波士顿地区的多家机构参与了认知节律合作项目，为发展数学、生物和认知科学领域的研究人员网络提供了一个独特的机会，以探索神经科学领域的迷人问题。这是一种不同于传统的互动机制，有可能改变处理此类跨学科问题的方式。该中心寻求通过在解决科学问题方面促进更广泛和更深层次的合作，提供开展科学研究的新途径。这项工作将涉及具有多种背景的科学家之间的紧密合作，并将强调数学在研究神经科学问题中的作用。该中心还将培养一批博士后，使他们对其工作的知识背景有深入的了解。该项目的技术核心将产生硬件和软件，这些硬件和软件将在CRC内外可用，并实现现在几乎不可能实现的计算。

This grant supports the Collaborative Rhythms Collaborative (CRC), a group of scientists in the Boston area who have begun to work together to advance our understanding of the brain dynamics underlying cognitive functions such as attention, sensation, motor planning, and memory. There is a growing consensus that dynamics are central to understanding how the brain works, but major gaps exist in what we know and in how we seek to understand more. The CRC has focused on the dynamical regime most strongly associated with cognition, rhythmic activity in the frequency range 1 - 200 Hz. Its central aims are to characterize the physiological origins and functions of such rhythms and to understand how pathologies in rhythmic dynamics are related to symptoms and mechanisms of neurological disease. Mathematical modeling, cutting-edge statistical techniques, and their implementation as computer algorithms will be critical to carrying out its scientific program. The grant will support the CRC, concentrating on the application of the mathematical sciences to the investigation of brain dynamics and the potential for new mathematical, statistical and computational techniques driven by challenging scientific problems. This will include support of a technology core that will create new hardware/software platforms to support such techniques. The CRC will also provide mentoring and teaching to a large community of students and post-doctoral fellows.The Cognitive Rhythms Collaborative, involving multiple institutions in the Boston area, offers a unique chance to develop a network of researchers from the mathematical, biological, and cognitive sciences to explore fascinating questions in the area of neuroscience. This is a different mechanism of interaction than is traditionally seen and has the potential to transform the way such interdisciplinary problems are addressed. The CRC seeks to provide new ways of doing science by fostering broader and deeper collaboration in addressing scientific questions. This work will involve tight collaborations among scientists with a multitude of backgrounds, and will emphasize the role of mathematics in the investigation of neuroscience questions. The CRC will also train a cohort of postdoctoral fellows in a way that will lead to a deep understanding of the intellectual context of their work. The technology core of the project will produce both hardware and software that will be available within and beyond the CRC, and enable computations that are now almost impossible.