Upgrade of a 600 MHz NMR Spectrometer at SUNY-ESF

凭借化学研究仪器和设施：部门多用户仪器计划（CRIF：MU）的这一奖项，纽约州立大学环境科学与林业学院的亚瑟·斯蒂帕诺维奇教授和同事将获得一个控制台和探针，以升级600 MHz核磁共振（NMR）光谱仪。该提案将加强各级的研究培训和教育，特别是在以下研究领域：（a）昆虫信息素研究，（B）细胞壁多糖的NMR，（c）天然产物的NMR，（d）NMR在生物炼制应用中的应用，（e）真核细胞液泡质子ATP酶定子结构域中的亚基结构和相互作用，以及（f）用于精细化学品和生物活性物质的可持续合成的新型生物催化结构。核磁共振（NMR）光谱是化学家可用于阐明分子结构的最有力的工具之一。它用于识别未知物质，跟踪化学反应的进展，表征分子内原子的特定排列，以及研究固体和溶液中分子之间相互作用的动力学。获得最先进的核磁共振光谱仪是必不可少的进行前沿化学相关的研究和培养学生的现代研究技术。这些NMR研究的结果将对SUNY-ESF的有机和生物有机化学研究产生影响。 该仪器将提供给其他机构的用户，包括锡拉丘兹大学，纽约州立大学北部医科大学和LeMoyne学院，并与区域公司合作。这些资源不仅将用于研究活动，而且还将用于本科生和研究生的研究培训，包括来自代表性不足群体的学生。

With this award from the Chemistry Research Instrumentation and Facilities: Departmental Multi-User Instrumentation program (CRIF:MU), Professor Arthur Stipanovic and colleagues from SUNY College of Environmental Science and Forestry will acquire a console and probes to upgrade a 600 MHz nuclear magnetic resonance (NMR) spectrometer. The proposal will enhance research training and education at all levels, especially in areas of study such as (a) insect pheromone research, (b) NMR of cell wall polysaccharides, (c) NMR of natural products, (d) NMR utilization in biorefinery applications, (e) subunit structure and interactions in the stator domain of the vacuolar proton-ATPase of eukarotyic cells, and (f) novel biocatalytic structures for the sustainable synthesis of fine chemicals and biologically active substances.Nuclear Magnetic Resonance (NMR) spectroscopy is one of the most powerful tools available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to follow the progress of chemical reactions, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solids and in solution. Access to state-of-the-art NMR spectrometers is essential to carry out frontier chemistry related research and to train students in modern research techniques. The results from these NMR studies will have an impact on organic and bioorganic chemistry research at SUNY-ESF. The instrument will be available to users at other institutions including Syracuse University, SUNY Upstate Medical University and LeMoyne College and for collaborations with regional companies. The resources will be used not only for research activities but also for research training of undergraduate and graduate students including those from underrepresented groups.