Patterning Vapor Deposited Polymers onto Porous Microfluidic Devices using Transition Metal Salts

使用过渡金属盐将气相沉积聚合物图案化到多孔微流体装置上

• 批准号: 1069328
• 负责人: Malancha Gupta
• 金额: $ 29.96万
• 依托单位: University of Southern California
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-03-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1069328&HistoricalAwards=false
• 关键词: Patterning; Vapor; Deposited; Polymers; onto

This grant provides funding to develop an environmentally benign vapor-phase patterning method for modifying the interfacial surface properties of three-dimensional porous materials. Metal salt inhibitors will be used to control the location of polymer growth. The fundamental mechanism behind the inhibition process and the generality of the patterning method will be studied by investigating the kinetics associated with the inhibition process as a function of substrate temperature, the flow rate of the precursors, and the time of deposition. The chemical interaction between the precursors and the inhibiting salts will be studied by examining the effects of changing the initiator and monomer molecules involved in the polymerization process. The uniformity of the inhibition through the depth of the porous materials will be studied as a function of the pore size and the mean free path. If successful, the results of this research will allow for the production of next-generation point-of-care paper-based diagnostic devices. The development of robust paper-based diagnostic devices is important for monitoring health-related issues in resource-limited environments such as personal homes and developing economies. This work will allow these devices to be patterned with a wide range of responsive and functional polymers that will greatly enhance their current analytical capabilities. This project will be used to mentor and train underrepresented high school and middle school students in downtown Los Angeles. The PI and the PI's students will work in collaboration with USC's MESA (Mathematics, Engineering, Science Achievement) program. The MESA program serves more than 1000 disadvantaged middle school and high school students in 23 schools in downtown Los Angeles.

该补助金提供资金，以开发一种环境友好的气相图案化方法，用于修改三维多孔材料的界面表面特性。金属盐抑制剂将用于控制聚合物生长的位置。抑制过程和图案化方法的一般性背后的基本机制将通过调查与抑制过程相关的动力学作为衬底温度，前体的流速和沉积时间的函数来研究。前体和抑制盐之间的化学相互作用将通过检查改变引发剂和单体分子在聚合过程中所涉及的影响进行研究。通过多孔材料的深度抑制的均匀性将作为孔径和平均自由程的函数进行研究。如果成功，这项研究的结果将允许生产下一代床旁纸基诊断设备。在资源有限的环境中，如个人家庭和发展中经济体，开发强大的纸基诊断设备对于监测健康相关问题非常重要。这项工作将使这些设备与广泛的响应和功能聚合物图案化，这将大大提高他们目前的分析能力。该项目将用于指导和培训洛杉矶市中心代表性不足的高中和初中学生。PI和PI的学生将与USC的梅萨（数学，工程，科学成就）计划合作。梅萨计划为洛杉矶市中心23所学校的1000多名弱势初中和高中学生提供服务。