Droplet Thermotaxis: A New Platform Technology for Droplet-based Microfluidic Systems

液滴趋热性：基于液滴的微流体系统的新平台技术

• 批准号: 1102280
• 负责人: Hyoung Jin Cho
• 金额: $ 36万
• 依托单位: The University of Central Florida Board of Trustees
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-05-01 至 2016-04-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1102280&HistoricalAwards=false
• 关键词: Droplet; Thermotaxis; New; Platform; Technology

Droplet Thermotaxis: A New Platform Technology for Droplet-based Microfluidic SystemsAbstractThe objective of this program is to develop a new platform technology for droplet-based microfluidic systems and demonstrate chemical unit operations using the developed platform for applications in chemistry and biology based on the study of the fundamental science of thermotaxis actuation. The intellectual merit is found at the cross-section of electrical engineering, mechanical engineering and chemistry, laying the solid foundation and design guidelines for various microfluidic devices and systems that can take advantage of the newly discovered droplet actuation mechanisms. The proposed work will provide fundamental information for understanding the dual behavior of droplets, underlying science of unique transport mechanisms at the interfacial boundaries (liquid-liquid, liquid-air, liquid-solid), practical tool kits for droplet-based chemical experiments, methodology for optical diagnostics of miniaturized devices and systems, and novel experimental protocols for controlled chemical reactions.The broader impacts are summarized as (a) wide applicability of our technology for handling liquid samples in a self-confined configuration and for the effective thermal management of droplets relevant to many disciplines (b) dissemination of cultivated knowledge to research communities across electrical engineering, mechanical engineering, chemistry and biology and (c) long-lasting educational outcomes from thoughtfully designed multidisciplinary mentorship and outreach activities involving undergraduate, graduate and K-12 students. This program is built upon a new and transformative discovery ? bidirectional droplet actuation based on the surface film deformation, unlike the traditional approach. This program will help understand the defining science and working principles so the newly proposed actuation mechanism may be favorably used for miniaturized devices and systems.

液滴趋热性：基于液滴的微流控系统的一种新的平台技术摘要本计划的目标是开发一种新的基于液滴的微流控系统的平台技术，并演示化学单元操作使用开发的平台在化学和生物学的基础上的趋热性驱动的基础科学的研究应用。在电气工程，机械工程和化学的横截面中发现了智力价值，为可以利用新发现的液滴驱动机制的各种微流体设备和系统奠定了坚实的基础和设计指南。 这项工作将为理解液滴的双重行为提供基础信息，为界面边界处独特的传输机制提供基础科学（液-液、液-气、液-固），用于液滴化学实验的实用工具包，用于微型化装置和系统的光学诊断的方法，和控制化学反应的新实验方案。更广泛的影响总结为：（a）我们的技术在自我处理液体样品中的广泛适用性，受限的配置和用于与许多学科相关的液滴的有效热管理（B）将培养的知识传播到电气工程，机械工程，化学和生物学，以及（c）长期-持久的教育成果，从精心设计的多学科指导和推广活动，涉及本科生，研究生和K-12学生。 这项计划是建立在一个新的和变革性的发现？与传统方法不同，基于表面膜变形的双向液滴驱动。该计划将有助于理解定义科学和工作原理，因此新提出的致动机构可以有利地用于小型化设备和系统。