Manipulation of plant defenses by an insect-vectored virus
通过昆虫传播的病毒操纵植物防御
基本信息
- 批准号:1121788
- 负责人:
- 金额:$ 38.11万
- 依托单位:
- 依托单位国家:美国
- 项目类别:Standard Grant
- 财政年份:2012
- 资助国家:美国
- 起止时间:2012-08-01 至 2015-07-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Infections with some plant-pathogenic viruses not only make the host plants more attractive for aphids, but also increase the rate of aphid growth and reproduction. This may represent active manipulation of plant metabolism by viruses, which rely on insects for their transmission from one plant to another. However, although numerous studies have demonstrated altered aphid growth on virus-infected plants, very little is known about the molecular mechanisms that underlie this phenomenon. Research using Arabidopsis thaliana (Arabidopsis), Myzus persicae (peach-potato aphid), and Turnip mosaic virus (TuMV) as a model system will be used to study the molecular biology of plant-aphid-virus interactions. Preliminary results show that Arabidopsis defense responses, which are normally turned on when aphids initiate feeding, are reduced in TuMV-infected plants. Further research will be directed at measuring virus-induced changes in plant metabolisms, identifying plant defense pathways that are manipulated by TuMV, and determining which of the eleven TuMV genes are required for shutting down anti-aphid defenses in Arabidopsis and other plant species.TuMV, which is commonly transmitted by green peach aphids, is a serious pathogen of vegetable crops. Virus control in agricultural systems is complicated by the propensity of peach-potato aphids to develop insecticide resistance, as well as TuMV reservoirs in Arabidopsis and other weed species. Research on the interactions of Arabidopsis, peach-potato aphids, and TuMV interactions, will identify previously unknown aspects of plant metabolism that contribute to aphid attraction and reproduction. Such information can be used to improve the insect and virus resistance of crop plants through classical breeding and transgenic approaches. The proposed project also will contribute to training a new generation of students in plant molecular biology, biochemistry, and genetics. These students will be well-prepared for future careers in the plant biotechnology industry, academia, or government service.
一些植物病原病毒的侵染不仅能使寄主植物对蚜虫更具吸引力,而且能提高蚜虫的生长和繁殖速度。这可能代表病毒对植物新陈代谢的主动操纵,病毒依靠昆虫从一种植物传播到另一种植物。然而,尽管许多研究已经证明蚜虫在病毒感染的植物上的生长发生了改变,但对这种现象背后的分子机制知之甚少。利用拟南芥(Arabidopsis thaliana)、桃蚜(Myzus persicae)和芜菁花叶病毒(TuMV)作为模型系统的研究将用于研究植物-蚜虫-病毒相互作用的分子生物学。初步结果表明,拟南芥防御反应,这是正常打开时,蚜虫开始进食,减少TuMV感染的植物。进一步的研究将致力于测量病毒诱导的植物代谢变化,鉴定TuMV操纵的植物防御途径,并确定11个TuMV基因中的哪些基因是关闭拟南芥和其他植物抗蚜虫防御所必需的。TuMV通常由绿色桃蚜传播,是蔬菜作物的严重病原体。农业系统中的病毒控制由于桃-马铃薯蚜虫发展杀虫剂抗性的倾向以及拟南芥和其他杂草物种中的TuMV水库而变得复杂。对拟南芥、桃-马铃薯蚜虫和TuMV相互作用的相互作用的研究,将确定以前未知的有助于蚜虫吸引和繁殖的植物代谢方面。这些信息可用于通过传统育种和转基因方法提高作物的抗虫性和抗病毒性。拟议的项目还将有助于培养新一代植物分子生物学、生物化学和遗传学学生。这些学生将为未来在植物生物技术行业,学术界或政府服务的职业生涯做好准备。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
Georg Jander其他文献
Natural variation of phytoalexin sakuranetin production in rice cultivars.
水稻品种中植物抗毒素樱素生产的自然变异。
- DOI:
- 发表时间:
2017 - 期刊:
- 影响因子:0
- 作者:
Takashige Kitano;Noriko Morimoto;Riko Yoshimoto;Sayaka Nishiguchi;Koichi Murata;Kotomi Ueno;Makoto Ueno;Yukinori Yabuta;Masayoshi Teraishi;Georg Jander;Yutaka Okumoto;Atsushi Ishihara - 通讯作者:
Atsushi Ishihara
Non-volatile metabolites mediate plant interactions with insect herbivores
- DOI:
- 发表时间:
2023 - 期刊:
- 影响因子:
- 作者:
Mei Luo;Bin Li;Georg Jander;Shaoqun Zhou - 通讯作者:
Shaoqun Zhou
RNAi-mediated silencing of endogenous Vlnv gene confers stable reduction of cold-induced sweetening in potato (Solanum tuberosum L. cv. Désirée)
- DOI:
10.1007/s11816-018-0482-y - 发表时间:
2018-04-05 - 期刊:
- 影响因子:1.600
- 作者:
Amir Hameed;Rakhshanda Bilal;Farooq Latif;Joyce Van Eck;Georg Jander;Shahid Mansoor - 通讯作者:
Shahid Mansoor
Interdependence of threonine, methionine and isoleucine metabolism in plants: accumulation and transcriptional regulation under abiotic stress
- DOI:
10.1007/s00726-010-0505-7 - 发表时间:
2010-02-26 - 期刊:
- 影响因子:2.400
- 作者:
Vijay Joshi;Je-Gun Joung;Zhangjun Fei;Georg Jander - 通讯作者:
Georg Jander
Two cysteines in each periplasmic domain of the membrane protein DsbB are required for its function in protein disulfide bond formation.
膜蛋白 DsbB 的每个周质结构域中的两个半胱氨酸是其在蛋白质二硫键形成中发挥功能所必需的。
- DOI:
- 发表时间:
1994 - 期刊:
- 影响因子:11.4
- 作者:
Georg Jander;Nancy L. Martin;Jon Beckwith - 通讯作者:
Jon Beckwith
Georg Jander的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('Georg Jander', 18)}}的其他基金
REU Site: Plant Genome Research
REU 网站:植物基因组研究
- 批准号:
1850796 - 财政年份:2019
- 资助金额:
$ 38.11万 - 项目类别:
Continuing Grant
IOS EDGE: Development of genetic and genomic resources for milkweed, Asclepias syriaca and Asclepias curassavica
IOS EDGE:马利筋、马利筋和马利筋遗传和基因组资源的开发
- 批准号:
1645256 - 财政年份:2017
- 资助金额:
$ 38.11万 - 项目类别:
Standard Grant
REU Site: Plant Genome Research
REU 网站:植物基因组研究
- 批准号:
1358843 - 财政年份:2014
- 资助金额:
$ 38.11万 - 项目类别:
Continuing Grant
Joint NSF/ERA-CAPS: Mechanisms of Natural Variation in Maize Herbivore Resistance
NSF/ERA-CAPS 联合研究:玉米食草动物抗性自然变异的机制
- 批准号:
1339237 - 财政年份:2014
- 资助金额:
$ 38.11万 - 项目类别:
Standard Grant
METABOLOMICS: Identification of inducible bioactive plant metabolites
代谢组学:诱导型生物活性植物代谢物的鉴定
- 批准号:
1139329 - 财政年份:2011
- 资助金额:
$ 38.11万 - 项目类别:
Continuing Grant
Arabidopsis 2010: Regulation of Branched-Chain Amino Acid Biosynthesis, a Paradigm for Studying Osmotic Stress Responses
拟南芥 2010:支链氨基酸生物合成的调节,研究渗透应激反应的范例
- 批准号:
1022017 - 财政年份:2010
- 资助金额:
$ 38.11万 - 项目类别:
Standard Grant
Dynamic Plant Responses to Aphid Infestation
植物对蚜虫侵染的动态反应
- 批准号:
0718733 - 财政年份:2007
- 资助金额:
$ 38.11万 - 项目类别:
Standard Grant
相似国自然基金
Molecular Plant
- 批准号:31224801
- 批准年份:2012
- 资助金额:20.0 万元
- 项目类别:专项基金项目
Molecular Plant
- 批准号:31024802
- 批准年份:2010
- 资助金额:20.0 万元
- 项目类别:专项基金项目
不同栽培环境条件下不同基因型牡丹根部细菌种群多样性特征
- 批准号:31070617
- 批准年份:2010
- 资助金额:30.0 万元
- 项目类别:面上项目
Journal of Integrative Plant Biology
- 批准号:31024801
- 批准年份:2010
- 资助金额:24.0 万元
- 项目类别:专项基金项目
植物病毒壳体"智能"纳米载体靶向肿瘤细胞的研究
- 批准号:30973685
- 批准年份:2009
- 资助金额:35.0 万元
- 项目类别:面上项目
南美蟛蜞菊入侵对土壤微生物的影响及反馈作用
- 批准号:30970556
- 批准年份:2009
- 资助金额:40.0 万元
- 项目类别:面上项目
弓形虫MAG嵌合型类病毒颗粒转基因植物快速高效表达技术平台的建立及其动物口服免疫机制的探索
- 批准号:30872204
- 批准年份:2008
- 资助金额:33.0 万元
- 项目类别:面上项目
梅花植株再生体系及遗传转化体系建立的研究
- 批准号:30371187
- 批准年份:2003
- 资助金额:7.0 万元
- 项目类别:面上项目
相似海外基金
Insect Espionage: Molecular Mechanisms of Caterpillar Subversion of Host Plant Defenses
昆虫间谍活动:毛毛虫颠覆宿主植物防御的分子机制
- 批准号:
RGPIN-2019-04516 - 财政年份:2022
- 资助金额:
$ 38.11万 - 项目类别:
Discovery Grants Program - Individual
Molecular mechanisms of pathogen adaptation to plant defenses
病原体适应植物防御的分子机制
- 批准号:
RGPIN-2017-05925 - 财政年份:2021
- 资助金额:
$ 38.11万 - 项目类别:
Discovery Grants Program - Individual
Insect Espionage: Molecular Mechanisms of Caterpillar Subversion of Host Plant Defenses
昆虫间谍活动:毛毛虫颠覆宿主植物防御的分子机制
- 批准号:
RGPIN-2019-04516 - 财政年份:2021
- 资助金额:
$ 38.11万 - 项目类别:
Discovery Grants Program - Individual
Elucidating the mechanisms by which the plant rhizosphere microbiome modulates systemic plant defenses
阐明植物根际微生物组调节植物系统防御的机制
- 批准号:
RGPIN-2016-04121 - 财政年份:2020
- 资助金额:
$ 38.11万 - 项目类别:
Discovery Grants Program - Individual
Molecular mechanisms of pathogen adaptation to plant defenses
病原体适应植物防御的分子机制
- 批准号:
RGPIN-2017-05925 - 财政年份:2020
- 资助金额:
$ 38.11万 - 项目类别:
Discovery Grants Program - Individual
Insect Espionage: Molecular Mechanisms of Caterpillar Subversion of Host Plant Defenses
昆虫间谍活动:毛毛虫颠覆宿主植物防御的分子机制
- 批准号:
RGPIN-2019-04516 - 财政年份:2020
- 资助金额:
$ 38.11万 - 项目类别:
Discovery Grants Program - Individual
Molecular mechanisms of pathogen adaptation to plant defenses
病原体适应植物防御的分子机制
- 批准号:
RGPIN-2017-05925 - 财政年份:2019
- 资助金额:
$ 38.11万 - 项目类别:
Discovery Grants Program - Individual
Insect Espionage: Molecular Mechanisms of Caterpillar Subversion of Host Plant Defenses
昆虫间谍活动:毛毛虫颠覆宿主植物防御的分子机制
- 批准号:
RGPIN-2019-04516 - 财政年份:2019
- 资助金额:
$ 38.11万 - 项目类别:
Discovery Grants Program - Individual
Elucidating the mechanisms by which the plant rhizosphere microbiome modulates systemic plant defenses
阐明植物根际微生物组调节植物系统防御的机制
- 批准号:
RGPIN-2016-04121 - 财政年份:2019
- 资助金额:
$ 38.11万 - 项目类别:
Discovery Grants Program - Individual
Elucidating the mechanisms by which the plant rhizosphere microbiome modulates systemic plant defenses
阐明植物根际微生物组调节植物系统防御的机制
- 批准号:
RGPIN-2016-04121 - 财政年份:2018
- 资助金额:
$ 38.11万 - 项目类别:
Discovery Grants Program - Individual