Collaborative Research: Abiotic Stress Combination: Bridging the gap between Arabidopsis Stress Research and Agriculture

合作研究：非生物胁迫组合：缩小拟南芥胁迫研究与农业之间的差距

• 批准号: 1137607
• 负责人: Ron Mittler
• 金额: --
• 依托单位: University of North Texas
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-09-01 至 2011-05-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1137607&HistoricalAwards=false
• 关键词: Collaborative; Research; Abiotic; Stress; Combination

Arabidopsis 2010: Abiotic stress combination: Bridging the gap between Arabidopsis stress research and agricultureThe work undertaken on this project is designed to make significant contributions to the goals of the 2010 program - to understand the networking and function of every gene in Arabidopsis. The specific focus of the project is on abiotic stress combinations and the genetic and metabolic networks that respond to stress combinations such as drought and heat, drought and salinity and salinity and heat. Abiotic stress is the primary cause of crop loss world-wide, with losses in the US estimated at 14-19 billion dollars each year. While abiotic stress is routinely studied in Arabidopsis by applying a single stress condition such as drought, salinity or heat, this type of analysis does not reflect the conditions that occur in the field where crop plants are subjected to a combination of different stresses. The central objective of the project is to identify novel genes, gene networks and metabolic pathways that specifically respond to a combination of two different abiotic stresses. The hypothesis to be tested is that dedicated genes, networks and pathways are activated in plants that are simultaneously exposed to two different stress conditions. This project is designed to bring Arabidopsis into the front line of applied research on abiotic stress tolerance, and bridge the gap between stress studies conducted with Arabidopsis in the lab and the conditions that impact crops in the field. The two key "Broader Impacts" of the proposed research are: 1) Development and maintenance of a centralized website that will bring together agronomists, breeders and Arabidopsis molecular biologists (http://www.ag.unr.edu/Stress_Combination/). 2) Educational outreach for K-12 and multidisciplinary training to postdoctoral, graduate and undergraduates trainees. Both undergraduate and K-12 outreach and training activities will target the under privileged and under represented in Science. Historically, abiotic stress combinations, such as drought and heat, had the outmost devastating economical and sociological impacts on the US, with losses of 48.4 and 61.6 billion dollars in 1980 and 1988 respectively. The proposed project will pave the way for the development of crops with enhanced abiotic stress tolerance, contributing to ameliorate the consequences of future weather disasters that are likely to increase in frequency due to anticipated climatic changes.

拟南芥2010：非生物应力组合：弥合拟南芥压力研究与该项目所做的农业工作之间的差距，旨在为2010年计划的目标做出重大贡献 - 了解拟南芥中每个基因的网络和功能。该项目的具体重点是对非生物应力组合以及对诸如干旱和热量，干旱，盐度以及盐度和热量等应力组合做出反应的遗传和代谢网络。非生物压力是全球农作物损失的主要原因，美国估计损失为14-190亿美元。虽然通过施加干旱，盐度或热量等单一应力条件，在拟南芥中常规研究非生物应力，但这种类型的分析并不能反映在作物植物遭受不同应力组合的田间发生的条件。该项目的核心目的是确定新的基因，基因网络和代谢途径，这些途径专门响应了两种不同的非生物胁迫的组合。要测试的假设是，专门的基因，网络和途径在同时暴露于两种不同应力条件的植物中被激活。该项目旨在将拟南芥带入有关非生物胁迫耐受性的应用研究的前线，并弥合实验室中用拟南芥进行的压力研究与影响野外作物的差异。拟议研究的两个关键“更广泛的影响”是：1）将农艺师，育种者和拟南芥分子生物学家（http://wwwwwww.ag.unr.unr.unr.unr.edu/sarts_combination/）汇总的集中式网站的开发和维护。 2）对博士后，研究生和本科生的K-12和多学科培训的教育宣传。本科生和K-12外展和培训活动都将针对科学的特权和不足。从历史上看，非生物压力组合（例如干旱和热量）对美国产生了最大的经济和社会学影响，在1980年和1988年分别损失了48.4和616亿美元。拟议的项目将为营造物质耐受性增强的农作物开发铺平道路，从而改善未来天气灾害的后果，由于预期的气候变化，频率可能会增加。