Instrument Development: Ultra-Sensitive, Single-Pass Electron Paramagnetic Resonance Spectrometers

仪器开发：超灵敏单通道电子顺磁共振波谱仪

• 批准号: 1152892
• 负责人: Pingshan Wang
• 金额: $ 38.42万
• 依托单位: Clemson University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-08-15 至 2017-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1152892&HistoricalAwards=false
• 关键词: Instrument; Development; Ultra; Sensitive; Single

In this award, funded by the Chemical Measurement and Imaging Program of the Division of Chemistry, Professor Pingshan Wang of Clemson University and his graduate students will be supported to develop an ultra-sensitive, single-pass electron paramagnetic resonance (EPR) spectrometer for the study of paramagnetic samples in the liquid phase. The instrument will utilize single-pass EPR sensors that exploit interference processes within the devices. The proposed instrument will be sensitive and fast - an order of magnitude better than current X-band spectrometers.EPR spectrometers are essential and powerful analytical tools for chemical studies. They may be used to detect the presence of electron spin in sample materials. Besides revealing the presence of unpaired electron spin (as in the case of reactive chemical species) the EPR spectra reveal unique details about the chemical environment, which help in understanding the molecular milieu around "spin labels". A key component of this research program is its educational objectives, which involve a number of students (from graduate school down to high school) who are engaged in scientific research. The instrument design that is developed through this research will be disseminated broadly through a website at Clemson University, as well as through The National Biomedical Research Center for AdvanCed ESR Technology (ACERT) at Cornell University.

在这项由化学系化学测量与成像计划资助的奖项中，克莱姆森大学的王平山教授及其研究生将获得支持，开发一台超灵敏、单程电子顺磁共振(EPR)光谱仪，用于研究液体中的顺磁样品。该仪器将使用单程EPR传感器，利用设备内的干扰过程。建议的仪器将是灵敏和快速的--比目前的X波段光谱仪好一个数量级。EPR光谱仪是化学研究必不可少的强大分析工具。它们可以用来检测样品材料中电子自旋的存在。除了揭示未配对电子自旋的存在(如在活性化学物种的情况下)，EPR谱还揭示了有关化学环境的独特细节，这有助于了解“自旋标签”周围的分子环境。这项研究计划的一个关键组成部分是它的教育目标，它涉及到许多从事科学研究的学生(从研究生到高中)。通过这项研究开发的仪器设计将通过克莱姆森大学的网站以及康奈尔大学的先进ESR技术国家生物医学研究中心(ACERT)广泛传播。