MRI: Acquisition of a Confocal Microscope for Multidisciplinary Research

蔡司LSM 700激光扫描共聚焦成像系统将用于肯纳索州立大学(KSU)生物物理、化学和生物化学系的多学科研究和教学，并将成为KSU新科学实验室大楼显微镜核心设施的支柱仪器。LSM 700和集成了Zen(蔡司高效导航)软件的工作站能够满足广泛的成像需求，从多重荧光和共定位分析到活细胞成像再到荧光团的光激活。这种灵活性将最大限度地增加可以利用显微镜的研究人员的数量和研究类型。共聚焦成像系统将推动KSU的研究计划，培育新的研究方向，并产生补充KSU研究人员使用的许多其他技术的数据，如荧光和标准显微镜、细胞培养和活体分析、凝胶移位、平衡饱和和竞争分析。LSM 700系统将增强KSU研究人员生成和解释数据的能力。将共焦结果与科罗拉多州立大学已经进行的实验相结合，将为科罗拉多州立大学及其合作机构正在进行的发育生物学、分子遗传学、神经生物学、植物学、生态学、进化生物学、生物化学和相关领域的研究提供重要的见解。虽然显微镜的主要用途将是研究，但它也将被纳入研究培训和课程课程。共聚焦显微镜是一种越来越常见的可视化生物和生化系统的研究工具。收购LSM 700共焦显微镜将对肯纳索州立大学(KSU)的研究环境产生重大影响，使生物与物理和化学与生物化学系的研究人员能够更全面地描述对他们所研究的系统重要的相互作用。科罗拉多州立大学教职员工结合共焦数据发表的创新研究将提供对细胞和发育生物学、生物化学、生态学、进化生物学和解剖学等领域的见解。此外，该仪器拓宽了KSU研究人员可用的研究工具阵列，使它们对更多研究密集型机构的科学家更具吸引力。除了主要的研究，教学实验将被设计为将共焦显微镜引入课堂。使用共焦显微镜将更定量的方法用于研究问题，也将使教师成为更好的教师，并为本科生提供宝贵的研究培训，包括代表人数不足的群体的成员。共聚焦成像技术和使用方面的实践培训将使KSU毕业生为STEM职业生涯做好更好的准备。

The Zeiss LSM 700 Laser Scanning Confocal Imaging System will be used in multidisciplinary research and education in the Departments of Biology & Physics and Chemistry and Biochemistry at Kennesaw State University (KSU) and will be the anchor instrument of KSU's microscopy core facility in the new Science Laboratory Building. The LSM 700 and integrated workstation with ZEN (Zeiss Efficient Navigation) software is capable of covering a broad range of imaging needs, from multiple fluorescence and co-localization analysis to live cell imaging to photoactivation of fluorophores. This flexibility will maximize the number of researchers, and types of research, that can make use of the microscope. The confocal imaging system will advance KSU research programs, foster new research directions, and generate data that will complement many other techniques employed by researchers at KSU, such as: fluorescent and standard microscopy, cell culture and in vivo assays, gel-shift, equilibrium saturation and competition assays. The LSM 700 system will enhance the ability of KSU researchers to generate and interpret data. The integration of confocal results with experiments already performed at KSU will provide crucial insights for on-going research in developmental biology, molecular genetics, neurobiology, botany, ecology, evolutionary biology, biochemistry, and related fields at KSU and our collaborator institutions. Although the primary use of the microscope will be for research, it will also be integrated into research training and course curricula. Confocal microscopy is an increasingly common research tool for visualizing biological and biochemical systems. Acquisition of the LSM 700 confocal microscope will have a significant impact on the research environment at Kennesaw State University (KSU), giving researchers in the Departments of Biology & Physics and Chemistry & Biochemistry the ability to more fully describe interactions important to the systems they study. Publication of innovative research by KSU faculty incorporating confocal data will provide insights into such fields as cell and developmental biology, biochemistry, ecology, evolutionary biology, and anatomy. In addition, the instrument broadens the array of research tools available to researchers at KSU and makes them more attractive collaborators for scientists at more research-intensive institutions. Beyond primary research, teaching experiments will be designed to incorporate confocal microscopy into the classroom. Bringing a more quantitative approach to bear on research problems using confocal microscopy will also make faculty better teachers and afford invaluable research training to undergraduates, including members of underrepresented groups. Hands-on training in the technology and usage of confocal imaging will better prepare KSU graduates for STEM careers.