MRI: Acquisition of an EPR spectrometer for studies in biochemistry, chemistry, and physics

马歇尔大学的Derrick Kolling教授及其同事Michael Norton、Michael Castellani、小平Sun和Nalini Santanam将获得一台电子顺磁共振（EPR）光谱仪，该光谱仪具有液氮和液氦冷却系统，能够分析3.8 K至室温的气相、液体或固相样品。该提案旨在加强各级的研究培训和教育，特别是在以下领域：(a)离子电荷转移磁体的合成和表征；(b)通过超高速冷冻淬火装置捕获的瞬态催化态；(c)利用光致ESP （LESR）表征DNA折纸实验台上的分子线和多分子组装；(d)铀酰UO2（2+）的化学和光化学还原；(e)稀释磁性半导体的研究；(f)氧化脂质在心血管疾病中的作用。EPR光谱仪产生分子和固态材料的几何和电子结构的详细信息。它还可用于获取自由基的寿命信息，这些自由基是参与有价值的化学转化以及病理性肿瘤生长起始的短命、高活性物质。这些研究将影响许多领域，从无机和有机分子的合成到新型固态材料的开发，再到磁性和生物化合物。从正在进行的研究中汲取灵感，该仪器将成为马歇尔大学和查尔斯顿大学本科和研究生阶段研究和教学的一个组成部分。

With this award from the Major Research Instrumentation Program, Professor Derrick Kolling from Marshall University and colleagues Michael Norton, Michael Castellani, Xiaoping Sun and Nalini Santanam will acquire an electron paramagnetic resonance (EPR) spectrometer with liquid nitrogen and liquid helium cooling systems and the capability of analyzing samples in the gas, liquid, or solid phases from 3.8 K up to room temperature. The proposal is aimed at enhancing research training and education at all levels, especially in areas such as (a) synthesis and characterization of ionic charge-transfer magnets; (b) transient catalytic states trapped via an ultrafast freeze-quench apparatus; (c) using light-induced ESP (LESR) to characterize molecular wires and multimolecular assemblies in a DNA origami testbed; (d) chemical and photochemical reduction of uranyl UO2(2+); (e) study in diluted magnetic semiconductor; and (f) oxidized lipids in cardiovascular disease.An EPR spectrometer yields detailed information on the geometric and electronic structure of molecular and solid state materials. It may also be used to obtain information about the lifetimes of free radicals, short-lived, highly reactive species involved in valuable chemical transformations as well as the initiation of pathological tumor growth. These studies will impact a number of areas, from the synthesis of inorganic and organic molecules to the development of new solid state materials to compounds of magnetic and biological interest. Employing examples inspired from ongoing research, this instrument will be an integral part of research and teaching at the undergraduate and graduate levels at Marshall University as well as at the University of Charleston.