SusChEM: RUI: Organohypervalent Iodine Chemistry

SusChEM:RUI:有机高价碘化学

基本信息

  • 批准号:
    1262479
  • 负责人:
  • 金额:
    $ 40.5万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
    Continuing Grant
  • 财政年份:
    2013
  • 资助国家:
    美国
  • 起止时间:
    2013-08-01 至 2017-07-31
  • 项目状态:
    已结题

项目摘要

In this project funded by the Chemical Synthesis Program of the Chemistry Division, Professor Viktor V. Zhdankin of the Department of Chemistry and Biochemistry at University of Minnesota Duluth will explore the chemistry of trivalent and pentavalent iodine compounds, which are efficient and environmentally benign oxidizing reagents with numerous applications in organic synthesis. While organohypervalent iodine compounds are well-established stoichiometric reagents, little progress has been made in the development of new catalytic reactions promoted by hypervalent iodine. Studies of new, metal-free catalytic reactions based on hypervalent iodine chemistry and an exploratory search for new and potentially useful organohypervalent iodine compounds are proposed. Synthetically useful methodologies based on the new, iodoarene-catalyzed oxidative transformations, such as the Hofmann rearrangement of amides to amines and the oxidative heterocyclization reactions leading to isoxazole derivatives and N-substituted indoles, will be investigated. Organoiodine-catalyzed enantioselective aziridination reactions on the basis of a recently discovered metal-free catalytic procedure for the aziridination of alkenes using organic iodide as catalyst will also be studied. An exploratory study on the preparation, structural characterization, and chemical properties of new, potentially useful hypervalent iodine amides, imides, and ylides will be also performed.New synthetic methodology based on organohypervalent iodine chemistry will contribute to environmentally benign methods for chemical synthesis as it utilizes non-toxic compounds of iodine as catalysts or recyclable reagents in aqueous solutions. Successful development of this methodology will have an impact on any area of activity in which the synthesis of molecules is needed, such as the pharmaceutical, chemical, agricultural industry, and the biological and chemical research activities. In addition, this project will provide excellent training of students, from pre-undergraduate to post-doctoral, including those from groups historically underrepresented in the sciences.
在这个由化学系化学合成项目资助的项目中,明尼苏达大学杜卢斯化学和生物化学系的Viktor V. Zhdankin教授将探索三价和五价碘化合物的化学,这些化合物是高效和环保的氧化剂,在有机合成中有许多应用。 虽然有机高价碘化合物是公认的化学计量试剂,但在高价碘促进的新催化反应的开发方面进展甚微。 提出了基于高价碘化学的新的无金属催化反应的研究以及对新的和潜在有用的有机高价碘化合物的探索性搜索。 合成有用的方法的基础上的新的,碘芳烃催化的氧化转化,如霍夫曼重排的酰胺胺和氧化杂环化反应,导致异恶唑衍生物和N-取代吲哚,将进行调查。 有机碘催化的对映选择性氮杂环丙烷化反应的基础上,最近发现的无金属催化程序的氮杂环丙烷化的烯烃使用有机碘化物作为催化剂也将进行研究。 此外,还将对具有潜在用途的高价碘酰胺、酰亚胺和叶立德的制备、结构表征和化学性质进行探索性研究。基于有机高价碘化学的新合成方法将有助于环境友好的化学合成方法,因为它利用无毒的碘化合物作为催化剂或水溶液中的可回收试剂。 这种方法的成功开发将对任何需要合成分子的活动领域产生影响,例如制药,化学,农业以及生物和化学研究活动。 此外,该项目将为学生提供优秀的培训,从大学预科到博士后,包括那些来自历史上在科学领域代表性不足的群体的学生。

项目成果

期刊论文数量(1)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Pseudocyclic Arylbenziodoxaboroles: Efficient Benzyne Precursors Triggered by Water at Room Temperature
  • DOI:
    10.1002/chem.201704393
  • 发表时间:
    2017-11-27
  • 期刊:
  • 影响因子:
    4.3
  • 作者:
    Yoshimura, Akira;Fuchs, Jonathan M.;Zhdankin, Viktor V.
  • 通讯作者:
    Zhdankin, Viktor V.
{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

数据更新时间:{{ journalArticles.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ monograph.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ sciAawards.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ conferencePapers.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ patent.updateTime }}

Viktor Zhdankin其他文献

Viktor Zhdankin的其他文献

{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

{{ truncateString('Viktor Zhdankin', 18)}}的其他基金

RUI: Development of New Reagents and Synthetic Methodologies Based on Hypervalent Iodine Chemistry
RUI:基于高价碘化学的新试剂和合成方法的开发
  • 批准号:
    2243793
  • 财政年份:
    2023
  • 资助金额:
    $ 40.5万
  • 项目类别:
    Standard Grant
RUI: Development of new polyvalent iodine reagents
RUI:新型多价碘试剂的开发
  • 批准号:
    1759798
  • 财政年份:
    2018
  • 资助金额:
    $ 40.5万
  • 项目类别:
    Standard Grant
RUI: Hypervalent Iodine Chemistry
RUI:高价碘化学
  • 批准号:
    1009038
  • 财政年份:
    2010
  • 资助金额:
    $ 40.5万
  • 项目类别:
    Continuing Grant
RUI: Chemistry of Hypervalent Organoiodine Compounds
RUI:高价有机碘化合物的化学
  • 批准号:
    0702734
  • 财政年份:
    2007
  • 资助金额:
    $ 40.5万
  • 项目类别:
    Continuing Grant
Acquisition of High Field NMR Spectrometer
购置高场核磁共振波谱仪
  • 批准号:
    0416157
  • 财政年份:
    2004
  • 资助金额:
    $ 40.5万
  • 项目类别:
    Standard Grant
Organic Chemistry of Hypervalent Compounds
高价化合物的有机化学
  • 批准号:
    0353541
  • 财政年份:
    2004
  • 资助金额:
    $ 40.5万
  • 项目类别:
    Standard Grant
RUI: Organic Chemistry of Hypervalent Compounds
RUI:高价化合物的有机化学
  • 批准号:
    0101021
  • 财政年份:
    2001
  • 资助金额:
    $ 40.5万
  • 项目类别:
    Standard Grant
New Polyvalent Iodine Reagents
新型多价碘试剂
  • 批准号:
    9802823
  • 财政年份:
    1998
  • 资助金额:
    $ 40.5万
  • 项目类别:
    Standard Grant
New Polyvalent Iodine Reagents
新型多价碘试剂
  • 批准号:
    9505868
  • 财政年份:
    1995
  • 资助金额:
    $ 40.5万
  • 项目类别:
    Standard Grant

相似海外基金

Collaborative Research: RUI: Continental-Scale Study of Jura-Cretaceous Basins and Melanges along the Backbone of the North American Cordillera-A Test of Mesozoic Subduction Models
合作研究:RUI:北美科迪勒拉山脊沿线汝拉-白垩纪盆地和混杂岩的大陆尺度研究——中生代俯冲模型的检验
  • 批准号:
    2346565
  • 财政年份:
    2024
  • 资助金额:
    $ 40.5万
  • 项目类别:
    Standard Grant
RUI: Spectroscopic Characterization and Low Temperature Kinetic Study of Hydrogenated Aromatic Radicals
RUI:氢化芳香族自由基的光谱表征和低温动力学研究
  • 批准号:
    2348916
  • 财政年份:
    2024
  • 资助金额:
    $ 40.5万
  • 项目类别:
    Standard Grant
RUI: Mechanoregulation of Collective Cell Migration in Biomimetic Microenvironments
RUI:仿生微环境中集体细胞迁移的机械调节
  • 批准号:
    2342274
  • 财政年份:
    2024
  • 资助金额:
    $ 40.5万
  • 项目类别:
    Standard Grant
Collaborative Research: RUI: Continental-Scale Study of Jura-Cretaceous Basins and Melanges along the Backbone of the North American Cordillera-A Test of Mesozoic Subduction Models
合作研究:RUI:北美科迪勒拉山脊沿线汝拉-白垩纪盆地和混杂岩的大陆尺度研究——中生代俯冲模型的检验
  • 批准号:
    2346564
  • 财政年份:
    2024
  • 资助金额:
    $ 40.5万
  • 项目类别:
    Standard Grant
RUI: Investigating the Covalency of Intermolecular Interactions and its Effect on the Properties of Supramolecular Complexes.
RUI:研究分子间相互作用的共价性及其对超分子复合物性质的影响。
  • 批准号:
    2404011
  • 财政年份:
    2024
  • 资助金额:
    $ 40.5万
  • 项目类别:
    Standard Grant
Collaborative Research: RUI: Glacier resilience during the Holocene and late Pleistocene in northern California
合作研究:RUI:北加州全新世和晚更新世期间的冰川恢复力
  • 批准号:
    2303409
  • 财政年份:
    2024
  • 资助金额:
    $ 40.5万
  • 项目类别:
    Standard Grant
Collaborative Research: RUI: IRES Track I: From fundamental to applied soft matter: research experiences in Mexico
合作研究:RUI:IRES 第一轨:从基础到应用软物质:墨西哥的研究经验
  • 批准号:
    2426728
  • 财政年份:
    2024
  • 资助金额:
    $ 40.5万
  • 项目类别:
    Standard Grant
RUI: Advancing the Organometallic Chemistry of Octahedral Re6 Clusters Containing Alkynyl Ligands
RUI:推进含有炔基配体的八面体 Re6 簇的有机金属化学
  • 批准号:
    2400260
  • 财政年份:
    2024
  • 资助金额:
    $ 40.5万
  • 项目类别:
    Standard Grant
Collaborative Research: RUI: Wave Engineering in 2D Using Hierarchical Nanostructured Dynamical Systems
合作研究:RUI:使用分层纳米结构动力系统进行二维波浪工程
  • 批准号:
    2337506
  • 财政年份:
    2024
  • 资助金额:
    $ 40.5万
  • 项目类别:
    Standard Grant
RUI: Collaborative Research: Assessing the causes of the pyrosome invasion and persistence in the California Current Ecosystem
RUI:合作研究:评估加州当前生态系统中火体入侵和持续存在的原因
  • 批准号:
    2329561
  • 财政年份:
    2024
  • 资助金额:
    $ 40.5万
  • 项目类别:
    Standard Grant
{{ showInfoDetail.title }}

作者:{{ showInfoDetail.author }}

知道了