Microfabricated Thermal Modulator for Comprehensive Two-Dimensional Gas Chromatography

用于综合二维气相色谱的微加工热调制器

• 批准号: 1305667
• 负责人: Katsuo Kurabayashi
• 金额: $ 25万
• 依托单位: Regents of the University of Michigan - Ann Arbor
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1305667&HistoricalAwards=false
• 关键词: Microfabricated; Thermal; Modulator; Comprehensive; Two

This research aims to develop a key microelectromechanical systems(MEMS) device necessary for low-power, low-cost, robust 2D GC. The specific objectives of thisproject are to (a) develop a good understanding of the physics and chemistry governing themicroscale thermal modulation based on theoretical modeling, (b) develop a new MEMS-basedthermal modulator (microTM) device design such that it enables a 2D GC system that achievestheoretically predicted maximum peak capacity and minimum peak breakthrough, (c) fabricate thedesigned ìTM and experimentally characterize its performance, and (d) finally, demonstrate micrTM incorporating2D GC with the highest compound separation performance with optimal operational conditions determined.Intellectual Merit: With the development of the microTM, our study will provide the first step towardsfully implementing comprehensive 2D GC with MEMS technology. It is readily conceivable that theimproved separation power of 2D GC systems would pave the way for highly reliable and accuratein-situ monitoring/detection of VOCs in a sample even containing complex co-contaminantbackgrounds. This project will make important contributions to micro analytical instrumentation forultimate use in field-deployable GC analyses.Broader Impact: Together with cost effectiveness, complete elimination of consumables from the 2D GCoperation with the microTM would fill the gap between the current relatively limited use and futuregeneral use of the 2D GC technique in a wide spectrum of applications, potentially opening newcommercial markets. The fundamental knowledge gained from this research will be assimilated intothe PI's graduate course on MEMS and chemical sensing. Summer interns from underrepresented groups will be trained through synergeticcoordination with the NSF National Nanotechnology Infrastructure Network (NNIN) program.

本研究的目的是开发一种关键的微机电系统（MEMS）设备所必需的低功耗，低成本，强大的二维GC。本项目的具体目标是：（a）基于理论建模，对控制微尺度热调制的物理和化学有很好的理解，（B）开发一种新的基于MEMS的热调制器（microTM）器件设计，使其能够实现理论上预测的最大峰容量和最小峰突破的2D GC系统，（c）制造所设计的microTM并实验表征其性能，（d）最后，在确定的最佳操作条件下，验证了micrTM微柱二维气相色谱仪具有最高的化合物分离性能。很容易想象，2D GC系统的改进分离能力将为高度可靠和准确的现场监测/检测样品中的VOC铺平道路，即使含有复杂的共污染物背景。该项目将为微型分析仪器的发展做出重要贡献，并最终用于现场可部署的GC分析。更广泛的影响：与成本效益一起，完全消除2D GC操作中的消耗品，microTM将填补2D GC技术在广泛应用中目前相对有限的使用和未来普遍使用之间的差距，潜在地打开新的商业市场。从这项研究中获得的基础知识将被吸收到PI的MEMS和化学传感研究生课程。来自代表性不足群体的暑期实习生将通过与NSF国家纳米技术基础设施网络（NNIN）计划的协同协调进行培训。