Investigating the Ability of Honey to Inhibit Bacterial Biofilms Found in Chronic Wounds

研究蜂蜜抑制慢性伤口中细菌生物膜的能力

• 批准号: LP0990949
• 负责人: Prof Elizabeth Harry
• 金额: $ 22.11万
• 依托单位: University of Technology Sydney
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Projects
• 财政年份: 2010
• 资助国家: 澳大利亚
• 起止时间: 2010-07-15 至 2013-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LP0990949
• 关键词: Investigating; Ability; Honey; Inhibit; Bacterial

Chronic (non-healing) wounds are a serious health problem in Australia. One quarter of our institutionalized aged population have pressure ulcers. The difficulty in treating these wounds is that most contain communities of bacteria, called biofilms, that are not killed by conventional antibiotics. Special honeys from Australia and NZ that are effective in chronic wound treatment can eradicate these biofilms. This project will identify the components in honey that do this and determine how they do it, to provide a more effective chronic wound treatment. It will decrease the prevalence of these wounds in Australia and the associated personal trauma and health costs.

慢性（不愈合）伤口是澳大利亚的一个严重健康问题。本港四分之一的院舍老人患有压力性溃疡。治疗这些伤口的困难在于，大多数伤口都含有被称为生物膜的细菌群落，这些细菌不会被常规抗生素杀死。来自澳大利亚和新西兰的特殊蜂蜜对慢性伤口治疗有效，可以消除这些生物膜。该项目将确定蜂蜜中的成分，并确定它们是如何做到这一点的，以提供更有效的慢性伤口治疗。它将减少澳大利亚这些伤口的流行率以及相关的个人创伤和健康成本。