Regulation of floral growth and patterning in Arabidopsis thaliana

拟南芥花生长和花型的调控

• 批准号: 1354452
• 负责人: Beth Krizek
• 金额: $ 81.97万
• 依托单位: University of South Carolina at Columbia
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-05-01 至 2022-04-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1354452&HistoricalAwards=false
• 关键词: Regulation; floral; growth; patterning; Arabidopsis

Beth KrizekIOS-1354452Regulation of floral growth and patterning in Arabidopsis thalianaFlowers initiate from the shoot apical meristem, a dome-shaped structure at the top of a plant that produces new organs throughout the plant's life. After outgrowth of a flower primordium from the meristem, floral organ primordia appear in characteristic positions within the flower and develop into one of four organ types: sepals, petals, stamens or carpels. Little is known about the mechanisms that control the positioning of floral organ initiation at particular locations within the flower and the means by which floral organs grow and develop into their characteristic forms. The experiments proposed here will investigate these little-understood aspects of plant development by studying two proteins that have partially overlapping functions in regulating gene expression within a flower. This project will use molecular and genetic approaches to investigate whether these proteins interact with each other and genomic approaches to identify genes that are regulated by these proteins. These studies will provide novel insights into pathways controlling the initiation and development of floral organs. As flowers give rise to essential components of the human diet, an understanding of how a flower is formed will contribute knowledge important for agricultural improvements needed to feed a growing world population. The collaborative nature of the project will provide interdisciplinary research experiences for students and a postdoctoral fellow in plant development, genomics and bioinformatics. The project will also provide a summer research internship for a high school teacher who will use this experience to develop inquiry-based learning modules.

Beth KrizekIOS-1354452拟南芥花的生长和模式的调节花起源于茎尖分生组织，这是一种位于植物顶部的圆顶状结构，在植物的整个生命周期中产生新的器官。花原基从分生组织中长出后，花器官原基出现在花内的特征位置，并发育成四种器官类型之一：萼片、花瓣、雄蕊或心皮。很少有人知道的机制，控制定位花器官起始在特定位置的花和花器官生长发育成其特征形式的手段。这里提出的实验将通过研究两种在调节花内基因表达方面具有部分重叠功能的蛋白质来研究植物发育的这些鲜为人知的方面。该项目将使用分子和遗传学方法来研究这些蛋白质是否相互作用，并使用基因组方法来识别受这些蛋白质调控的基因。这些研究将为控制花器官启动和发育的途径提供新的见解。由于花卉是人类饮食的重要组成部分，了解花卉是如何形成的将有助于为养活不断增长的世界人口所需的农业改进提供重要知识。该项目的合作性质将为学生和植物发育，基因组学和生物信息学的博士后研究员提供跨学科的研究经验。该项目还将为一名高中教师提供暑期研究实习机会，该教师将利用这一经验开发基于探究的学习模块。