MRI: Acquisition of a 400 MHz NMR Spectrometer to Support Research and Undergraduate Research Training at Carleton College and St. Olaf College

MRI：购买 400 MHz NMR 波谱仪以支持卡尔顿学院和圣奥拉夫学院的研究和本科生研究培训

• 批准号: 1428752
• 负责人: Gretchen Hofmeister
• 金额: $ 33.55万
• 依托单位: Carleton College
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-08-01 至 2017-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1428752&HistoricalAwards=false
• 关键词: MRI; Acquisition; 400; MHz; NMR

With this award from the Major Research Instrumentation Program (MRI) and support from the Chemistry Research Instrumentation Program (CRIF), Professor Gretchen Hofmeister from Carleton College and colleagues David Alberg and Matthew Whited will acquire a 400 MHz NMR spectrometer with field gradient capabilities for two-dimensional and dynamic NMR experiments. This spectrometer will allow research in a variety of fields such as those that accelerate chemical reactions of significant economic importance, as well as allow study of biologically relevant species. In general, Nuclear Magnetic Resonance (NMR) spectroscopy is one of the most powerful tools available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectrometers is essential to chemists who are carrying out frontier research. The results from these NMR studies will have an impact in synthetic organic/inorganic chemistry, materials chemistry and biochemistry. This instrument will be an integral part of teaching as well as research performed by undergraduate students at Carleton College and St. Olaf College. The award is aimed at enhancing research and education at all levels, especially in areas such as (a) studies of trypanothione reductase inhibitors; (b) synthesis and applications of extended linear chain (ELC) materials; (c) studies of titanium(IV) trisphenolate catalysts; (d) organocatalysis; (e) studies of metal/ligand cooperative reactivity; and (f) synthesis and structure of Mo(II) acetyl complexes.

在主要研究仪器计划(MRI)的这一奖项和化学研究仪器计划(CRIF)的支持下，来自卡尔顿学院的Gretchen Hofmeister教授及其同事David Alberg和Matthew Whited将获得一台具有场梯度功能的400 MHz核磁共振光谱仪，用于二维和动态核磁共振实验。这种光谱仪将允许在各种领域进行研究，例如那些加速具有重大经济意义的化学反应的领域，以及允许研究与生物相关的物种。总的来说，核磁共振波谱是化学家用来阐明分子结构的最强大的工具之一。它被用来识别未知物质，表征分子内原子的特定排列，并研究溶液中分子之间相互作用的动力学。对于正在进行前沿研究的化学家来说，获得最先进的核磁共振光谱仪是必不可少的。这些核磁共振研究的结果将对合成有机/无机化学、材料化学和生物化学产生影响。该乐器将是卡尔顿学院和圣奥拉夫学院的本科生进行的教学和研究的一个组成部分。该奖项旨在加强各级的研究和教育，特别是在以下领域：(A)锥硫酮还原酶抑制剂的研究；(B)扩展直链(ELC)材料的合成和应用；(C)钛(IV)三酚催化剂的研究；(D)有机催化；(E)金属/配体合作反应的研究；(F)钼(II)乙酰基配合物的合成和结构。

项目成果

Computational and Experimental Investigation of Alkene Hydrogenation by a Pincer-Type [P 2 Si]Rh Complex: Alkane Release via Competitive σ-Bond Metathesis and Reductive Elimination

钳型 [P 2 Si]Rh 配合物对烯烃加氢的计算和实验研究：通过竞争性 Ï 键复分解和还原消除释放烷烃

• DOI: 10.1021/acs.organomet.8b00922
• 发表时间: 2019
• 期刊: Organometallics
• 影响因子: 2.8
• 作者: Whited, Matthew T.;Trenerry, Michael J.;DeMeulenaere, Kaitlyn E.;Taylor, Buck L.
• 通讯作者: Taylor, Buck L.

Cooperative CO 2 Scission by Anomalous Insertion into a Rh–Si Bond

通过反常插入RhâSi 键的协同CO 2 断裂

• DOI: 10.1021/acs.organomet.9b00556
• 发表时间: 2019
• 期刊: Organometallics
• 影响因子: 2.8
• 作者: Whited, Matthew T.;Zhang, Jia;Donnell, Theodore M.;Eng, Vanessa H.;Peterson, Paul O.;Trenerry, Michael J.;Janzen, Daron E.;Taylor, Buck L.
• 通讯作者: Taylor, Buck L.