NNCI: Soft and Hybrid Nanotechnology Experimental (SHyNE) Resource

软混合纳米技术实验 (SHyNE) 资源 NNCI 站点是西北大学 (NU) 和芝加哥大学 (UC) 之间的合作项目，建立在两所机构改变科学和工程前沿的悠久历史之上。软纳米结构本质上通常是聚合的、生物的和流体的，而混合代表包含软-硬界面的系统。 SHyNE 设施能够通过多方面和跨学科的方法实现变革性科学和支持技术，从而广泛访问广泛的制造、表征和计算基础设施。除了传统的微/纳米制造工具外，SHyNE 还提供软材料和软硬混合纳米系统的专业功能。 SHyNE 通过为用户提供现场和远程开放访问最先进的实验室和世界一流的技术专业知识来增强区域能力，帮助解决农业、生物医学、化学、食品、地质和环境等非传统领域纳米技术研发中的挑战性问题。 SHyNE 使命的一个重要组成部分是通过中学和高等教育的研究经验以及与两所大学课程的整合来进行学术推广，以及通过与梅迪尔新闻学院合作的新型纳米新闻项目来进行社会推广。 SHyNE 促进包括妇女和少数族裔在内的弱势群体积极参与科学领域，并利用芝加哥的公共博物馆进行更广泛的宣传。 SHyNE 利用深厚的知识、学术和设施资源，提供关键基础设施来支持纳米科学和纳米技术的研究、应用开发和问题解决，并将这种变革性方法融入芝加哥和大中西部地区的社会结构。SHyNE 是一项以解决方案为中心的开放式协作计划，在 NU 国际纳米技术研究所 (IIN) 的支持下与加州大学分子工程研究所 (IME) 合作运营。 SHyNE 开放访问用户设施汇集了传统软纳米材料（例如生物、聚合物或流体系统以及结合软/硬材料和界面的混合系统）的广泛经验和能力。总的来说，软纳米结构和混合纳米结构代表了非凡的科学和技术机遇。然而，考虑到 100 纳米以下的长度和相关的复杂性，需要先进的设施来充分发挥其潜力。此类设施需要能够在大面积上对软/混合纳米结构进行图案化，并需要工具/技术来表征它们的原始状态。 SHyNE 满足了这些不同但综合的需求，因为它将 NU 广泛的冷冻生物、表征和软纳米图案能力与加州大学普利兹克纳米加工设施 (PNF) 的最先进的洁净室制造和专业知识相协调。 SHyNE 解决了软/生物结构的合成/组装以及经典洁净室功能与软生物结构集成方面的新兴需求，提供与肽和肽基材料的合成、纯化和表征相关的专业知识和仪器。 SHyNE 与阿贡国家实验室设施进行协调，并分别利用分层材料设计中心 (CHiMaD) 和数字制造与设计创新研究所 (DMDII) 下的现有超级计算和工程专业知识。一系列广泛的创新教育、行业和社会推广活动，例如纳米新闻、以行业为中心的研讨会/研讨会以及与芝加哥地区博物馆的合作，为下一代研究人员和更广泛的社会提供了软/混合系统现代基础设施的综合和全面覆盖。

The Soft and Hybrid Nanotechnology Experimental (SHyNE) Resource NNCI site is a collaborative venture between Northwestern University (NU) and the University of Chicago (UC), building upon each institution's long history of transforming the frontiers of science and engineering. Soft nanostructures are typically polymeric, biological and fluidic in nature while hybrid represents systems comprising soft-hard interfaces. SHyNE facilities enable broad access to an extensive fabrication, characterization and computational infrastructure with a multi-faceted and interdisciplinary approach for transformative science and enabling technologies. In addition to traditional micro/nanofabrication tools, SHyNE provides specialized capabilities for soft materials and soft-hard hybrid nano-systems. SHyNE enhances regional capabilities by providing users with on-site and remote open-access to state-of-the-art laboratories and world-class technical expertise to help solve the challenging problems in nanotechnology research and development for non-traditional areas such as the agricultural, biomedical, chemical, food, geological and environmental, among other industries. A critical component of the SHyNE mission is scholarly outreach through secondary and post-secondary research experience and integration with curricula at both universities, as well as, societal outreach through a novel nano-journalism project in collaboration with the Medill School of Journalism. SHyNE promotes active participation of underrepresented groups, including women and minorities, in sciences and utilizes Chicago's public museums for broader outreach. SHyNE leverages an exceptional depth of intellectual, academic and facilities resources to provide critical infrastructure in support of research, application development and problem-solving in nanoscience and nanotechnology and integrates this transformative approach into the societal fabric of Chicago and the greater Midwest.SHyNE is a solution-focused, open-access collaborative initiative operating under the umbrella of NU's International Institute for Nanotechnology (IIN), in partnership with UC's Institute for Molecular Engineering (IME). SHyNE open-access user facilities bring together broad experience and capabilities in traditional soft nanomaterials such as biological, polymeric or fluidic systems and hybrid systems combining soft/hard materials and interfaces. Collectively, soft and hybrid nanostructures represent remarkable scientific and technological opportunities. However, given the sub-100nm length-scale and related complexities, advanced facilities are needed to harness their full potential. Such facilities require capabilities to pattern soft/hybrid nanostructures across large areas and tools/techniques to characterize them in their pristine states. These divergent yet integrated needs are met by SHyNE, as it coordinates NU's extensive cryo-bio, characterization and soft-nanopatterning capabilities with the state-of-the-art cleanroom fabrication and expertise at UC's Pritzker Nanofabrication Facility (PNF). SHyNE addresses emerging needs in synthesis/assembly of soft/biological structures and integration of classical clean-room capabilities with soft-biological structures, providing expertise and instrumentation related to the synthesis, purification, and characterization of peptides and peptide-based materials. SHyNE coordinates with Argonne National Lab facilities and leverages existing super-computing and engineering expertise under Center for Hierarchical Materials Design (CHiMaD) and Digital Manufacturing and Design Innovation Institute (DMDII), respectively. An extensive array of innovative educational, industry and societal outreach, such as nano-journalism, industry-focused workshop/symposia and collaborations with Chicago area museums, provide for an integrated and comprehensive coverage of modern infrastructure for soft/hybrid systems for the next generation researchers and the broader society.