NNCI: Soft and Hybrid Nanotechnology Experimental (SHyNE) Resource

软和混合纳米技术实验（SHyNE）资源NNCI站点是西北大学（NU）和芝加哥大学（UC）之间的合作项目，建立在两所大学在改变科学和工程前沿的悠久历史之上。软纳米结构在本质上是典型的聚合物、生物和流体，而混合纳米结构则代表由软硬界面组成的系统。SHyNE设施可以广泛访问广泛的制造，表征和计算基础设施，采用多方面和跨学科的方法进行变革科学和使能技术。除了传统的微/纳米加工工具外，SHyNE还提供软材料和软硬混合纳米系统的专业能力。SHyNE通过为用户提供现场和远程开放访问最先进的实验室和世界一流的技术专长来增强区域能力，帮助解决非传统领域（如农业、生物医学、化学、食品、地质和环境等行业）的纳米技术研究和开发中的挑战性问题。SHyNE使命的一个关键组成部分是通过中学和大专研究经验进行学术推广，并与两所大学的课程相结合，以及通过与Medill新闻学院合作的新颖纳米新闻项目进行社会推广。SHyNE促进包括妇女和少数民族在内的代表性不足的群体积极参与科学，并利用芝加哥的公共博物馆进行更广泛的宣传。SHyNE利用卓越的智力、学术和设施资源深度，为纳米科学和纳米技术的研究、应用开发和解决问题提供关键基础设施，并将这种变革方法整合到芝加哥和中西部地区的社会结构中。SHyNE是北大国际纳米技术研究所（IIN）与加州大学分子工程研究所（IME）合作开展的一项以解决方案为重点的开放获取合作计划。SHyNE开放访问用户设施汇集了传统软纳米材料（如生物，聚合物或流体系统）和结合软/硬材料和界面的混合系统的广泛经验和能力。总的来说，软纳米结构和混合纳米结构代表着非凡的科学和技术机遇。然而，考虑到100nm以下的长度尺度和相关的复杂性，需要先进的设施来充分利用其潜力。这样的设施需要在大范围内对软/混合纳米结构进行建模的能力，以及在原始状态下对其进行表征的工具/技术。SHyNE可以满足这些不同但综合的需求，因为它将NU广泛的冷冻生物，表征和软纳米图形能力与UC普利兹克纳米制造设施（PNF）的最先进的洁净室制造和专业知识相结合。SHyNE解决了软/生物结构合成/组装的新兴需求，并将经典的洁净室能力与软生物结构相结合，提供与肽和肽基材料的合成、纯化和表征相关的专业知识和仪器。SHyNE与阿贡国家实验室设施协调，并利用分层材料设计中心（CHiMaD）和数字制造与设计创新研究所（DMDII）现有的超级计算和工程专业知识。一系列创新的教育、工业和社会外展活动，如纳米新闻、以工业为重点的研讨会/专题讨论会以及与芝加哥地区博物馆的合作，为下一代研究人员和更广泛的社会提供了软/混合系统的现代基础设施的综合和全面覆盖。

The Soft and Hybrid Nanotechnology Experimental (SHyNE) Resource NNCI site is a collaborative venture between Northwestern University (NU) and the University of Chicago (UC), building upon each institution's long history of transforming the frontiers of science and engineering. Soft nanostructures are typically polymeric, biological and fluidic in nature while hybrid represents systems comprising soft-hard interfaces. SHyNE facilities enable broad access to an extensive fabrication, characterization and computational infrastructure with a multi-faceted and interdisciplinary approach for transformative science and enabling technologies. In addition to traditional micro/nanofabrication tools, SHyNE provides specialized capabilities for soft materials and soft-hard hybrid nano-systems. SHyNE enhances regional capabilities by providing users with on-site and remote open-access to state-of-the-art laboratories and world-class technical expertise to help solve the challenging problems in nanotechnology research and development for non-traditional areas such as the agricultural, biomedical, chemical, food, geological and environmental, among other industries. A critical component of the SHyNE mission is scholarly outreach through secondary and post-secondary research experience and integration with curricula at both universities, as well as, societal outreach through a novel nano-journalism project in collaboration with the Medill School of Journalism. SHyNE promotes active participation of underrepresented groups, including women and minorities, in sciences and utilizes Chicago's public museums for broader outreach. SHyNE leverages an exceptional depth of intellectual, academic and facilities resources to provide critical infrastructure in support of research, application development and problem-solving in nanoscience and nanotechnology and integrates this transformative approach into the societal fabric of Chicago and the greater Midwest.SHyNE is a solution-focused, open-access collaborative initiative operating under the umbrella of NU's International Institute for Nanotechnology (IIN), in partnership with UC's Institute for Molecular Engineering (IME). SHyNE open-access user facilities bring together broad experience and capabilities in traditional soft nanomaterials such as biological, polymeric or fluidic systems and hybrid systems combining soft/hard materials and interfaces. Collectively, soft and hybrid nanostructures represent remarkable scientific and technological opportunities. However, given the sub-100nm length-scale and related complexities, advanced facilities are needed to harness their full potential. Such facilities require capabilities to pattern soft/hybrid nanostructures across large areas and tools/techniques to characterize them in their pristine states. These divergent yet integrated needs are met by SHyNE, as it coordinates NU's extensive cryo-bio, characterization and soft-nanopatterning capabilities with the state-of-the-art cleanroom fabrication and expertise at UC's Pritzker Nanofabrication Facility (PNF). SHyNE addresses emerging needs in synthesis/assembly of soft/biological structures and integration of classical clean-room capabilities with soft-biological structures, providing expertise and instrumentation related to the synthesis, purification, and characterization of peptides and peptide-based materials. SHyNE coordinates with Argonne National Lab facilities and leverages existing super-computing and engineering expertise under Center for Hierarchical Materials Design (CHiMaD) and Digital Manufacturing and Design Innovation Institute (DMDII), respectively. An extensive array of innovative educational, industry and societal outreach, such as nano-journalism, industry-focused workshop/symposia and collaborations with Chicago area museums, provide for an integrated and comprehensive coverage of modern infrastructure for soft/hybrid systems for the next generation researchers and the broader society.